MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Breaking Away From the Ivory Tower

    J. de (Kogarah, Australia)

    Objective: We describe the evolution of the Geriatric Flying Squad (GFS), a rapid response outreach team for residential aged care facilities (RACFs) in the local…
  • 2025 International Congress

    Disease Monitoring through the PKAN Disease Rating Scale (PKAN-DRS) in Pantothenate Kinase-Associated Neurodegeneration (PKAN)

    A. Salazar-Villacorta, R. Spaull, M. Correa-Vela, A. Cazurro, J. Ferrero Turión, A. Soo, M. González, A. Macaya, B. Pérez-Dueñas, M. Kurian (London, United Kingdom)

    Objective: To assess the utility of PKAN-DRS as an outcome measure for monitoring disease progression in PKAN . Background: The PKAN-DRS assess multiple domains affected…
  • 2025 International Congress

    Oligodendrocyte-specific mRNA therapy with lipid nanoparticles

    M. Sawamura, K. Tachikawa, R. Hikawa, H. Yamakado, R. Takahashi, S. Matsuzawa (San Diego, USA)

    Objective: To develop lipid nanoparticles with high efficiency and specificity to introduce mRNA into oligodendrocytes. To denmonstrate the potential therapy of Krabbe disease as one…
  • 2025 International Congress

    Archimedes spiral based non-linear regression machine learning model for predicting tremor’s severity

    A. Rekik, S. Laatoui, M. Abid, R. Guizani, I. Rekik, S. Ben Amor (Sousse, Tunisia)

    Objective: To predict tremor severity using the Archimedes spiral drawing, a commonly used item in tremor assessment scales. Background: The Archimedes spiral is widely used…
  • 2025 International Congress

    Multimodal and Agentic Simulated AI Patients for Bridging the gap in Parkinson Disease Education

    L. Okar, M. Fani (St. Louis, USA)

    Objective: To develop an AI training platform in PD counseling that utilizes real-time NLP processing, multimodal inputs/outputs, and adaptive reinforcement learning supported by immediate feedback…
  • 2025 International Congress

    A Randomized, Double-blind Phase 3 Trial of Amlenetug Versus Placebo in Patients with MSA: The MASCOT Trial

    L. Kjærsgaard, M. Nørbæk Jørgensen, S. Zanigni, J. Wiedemann, J. Luthman (Valby, Denmark)

    Objective: Describe the protocol for a randomized, double-blind phase 3 trial evaluating the efficacy and safety of amlenetug versus placebo in slowing clinical progression in…
  • 2025 International Congress

    Effects of transcutaneous periodic vibratory stimulation on gait and balance function in Spinocerebellar degeneration -a pilot study

    N. Togashi, S. Kubokawa, K. Minemura, K. Tateno, Y. Miyagi, A. Kawanami, K. Hasegawa (Sagamihara, Japan)

    Objective: The aim of this study is to clarify the efficacy of transcutaneous periodic vibrational stimulation(TPVS)on gait and balance function in patients with spinocerebellar degeneration…
  • 2025 International Congress

    Clinical case of Sporadic adult-onset ataxia

    N. Aripova, L. Kenjaeva, B. Bakhtiyor, Y. Nishonova (Tashkent, Uzbekistan)

    Objective: To describe a clinical case of Sporadic adult-onset ataxia(SAOA) Background: Sporadic ataxia in adults is a heterogeneous neurological condition characterized by progressive impairment of…
  • 2025 International Congress

    Refractory Orthostatic Hypotension, Anterocollis Predominant Cervical Dystonia and Parkinsonism Associated with a Previously Undiscovered SYT14 Gene Mutation

    W. Gan, O. Carranza-Renteria, T. Fistel, S. Husain-Wilson (Boca Raton, USA)

    Objective: We present a case of a patient with spinocerebellar ataxia symptoms associated with a previously unknown mutation of the SYT14 gene. Background: Spinocerebellar ataxias…
  • 2025 International Congress

    Retrospective Analysis of our Supportive Care Clinic and Lifestyle Improvement Fitness Program

    N. Hellmers, A. Weiss, B. Katz, S. Fine, A. Aminpour, A. Yoo, H. Ooi, H. Sarva (New York, USA)

    Objective: The Supportive Care Clinic and Lifestyle Improvement Fitness (LIFT) program provides multidisciplinary care and online educational resources for our parkinsonian patients. Demographics of patients…
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