Explore cellular heterogeneities of orbitofrontal cortex in multiple system atrophy using spatial transcriptomics
Objective: To explore the spatial organization and cellular complexity of the orbitofrontal cortex (OFC) in multiple system atrophy (MSA) via spatial transcriptomic (SRT). Background: The…Lyme disease presenting as a rapidly progressive MSA-C look alike
Objective: We report two cases of encephalomyelitis due to Lyme disease with cerebellar ataxia and autonomic symptoms, which presented with a rapidly progressive MSA-like phenotype.…Apathy produces selective deficits in cognitive function when controlling for depression in patients with Parkinson’s disease
Objective: To compare differences in the mean cognitive impairment (CI) of patients with and without clinically significant apathy in PD, PD-mild cognitive impairment (PD-MCI), and…Creating a Multi-institutional, Interdisciplinary Functional Neurological Disorder (FND) Clinic in an Urban Setting
Objective: To describe the process to create an interdisciplinary FND clinic with independent practitioners in the New York City area. Background: Estimated 9,000 people in…Increased Resting Anterior Hippocampus Metabolism and Hippocampus Subfields Structural Abnormalities in Functional Tremor Patients: FDG- PET Study and Volumetric MRI Study
Objective: In this study, we focused on identifying the resting 18F-FDG PET brain imaging patterns in the limbic region and measuring the MRI volumes of…Safety of Pimavanserin for Parkinson’s Disease Psychosis: Exploratory Analysis of Sedation and Sleep Data From Clinical Studies
Objective: To summarize the sleep and sedation-related safety and tolerability of pimavanserin for the treatment of Parkinson’s disease psychosis (PDP). Background: Pimavanserin, a 5-HT2A receptor…Longitudinal patterns of Anxiety and Depression in patients with Parkinson’s Disease
Objective: To analyze longitudinal trends of severity of anxiety and depression in a large Parkinson’s Disease (PD) cohort Background: •Depression and anxiety are common non…Gastrointestinal Dysbiosis and Clinical Outcomes in Parkinson’s Disease
Objective: To evaluate whether patients with PD exhibit 1) a bloom in sulfate-reducing bacteria based on the detection of hydrogen-sulfide (H2S) during lactulose breath testing…Behavioral health characteristics of pre-surgical Focused Ultrasound and Deep Brain Stimulation candidates
Objective: To characterize psychological traits in patients who pursue focused ultrasound (FUS) versus deep brain stimulation (DBS) for tremor management Background: Psychosocial characteristics can determine…Phenomenology of Functional Movement Disorders in Children
Objective: To study the phenomenology of Functional Movement Disorders (FMD) in children. Background: Data on FMD in children is sparse Method: The study included 13…
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