MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    All-cause mortality in pimavanserin and atypical antipsychotic users with Parkinson’s disease in Medicare

    A. Mosholder, Y. Ma, S. Akhtar, G. Podskalny, Y. Wei, J. Liao, Y. Feng, H. Lyu, M. Wernecke, K. Leishear, L. Nelson, T. MaCurdy, J. Kelman, D. Graham (Silver Spring, MD, USA)

    Objective: To assess all-cause mortality in Medicare beneficiaries with Parkinson’s disease (PD)  receiving pimavanserin or atypical antipsychotics (AAs). Background: In PD patients, the lifetime prevalence…
  • MDS Virtual Congress 2020

    New compound increasing glucocerebrosidase activity on primary cell cultures obtained from patients with GBA-associated Parkinson’s disease

    M. Nikolaev, A. Kopytova, K. Senkevich, G. Baydakova, I. Miliukhina, E. Zakharova, G. Rychkov, A. Cheblokov, F. Ibatullin, S. Pchelina, A. Emelyanov (Gatchina, Russian Federation)

    Objective: To determine whether new chemical modifications of the previously described allosteric GCase chaperone N607 (Aflaki E et.al Neurosc. 2016) increase GCase activity in monocyte-derived…
  • MDS Virtual Congress 2020

    Pharmacokinetics of Levodopa in patients with Parkinson’s disease: Efforts toward a predictive model

    N. Nishikawa, H. Iwaki, T. Shiraishi, Y. Mukai, Y. Takahashi, N. Hattori (Kodaira, Japan)

    Objective: Our aim was to explore correlations between the pharmacokinetics of levodopa (LD) and clinical manifestation in patients with Parkinson’s disease (PD). Our goal was…
  • MDS Virtual Congress 2020

    A Case of Improved Psychotic Depression and Motor Symptoms in Parkinson’s Disease following Electroconvulsive Therapy (ECT)

    S. Ramesh, J. Ratliff (Philadelphia, PA, USA)

    Objective: To describe a case of motoric, affective, and psychotic symptoms improving in PD following ECT. Background: Parkinson’s disease (PD) is a neurodegenerative disease caused…
  • MDS Virtual Congress 2020

    Effectiveness and Tolerability of Mirabegron and Behavioral Therapy in Patients with Parkinson’s Disease and Overactive Bladder: A Prospective, Randomized, Placebo-Controlled Pilot Study

    S. Ray, D. Burdick, P. Agarwal, A. Madan (Kirkland, WA, USA)

    Objective: To assess safety, tolerability, and efficacy of mirabegron and Pelvic floor Exercise (PFE)-based behavioral therapy for the treatment of overactive bladder (OAB) in patients…
  • MDS Virtual Congress 2020

    Noninvasive brain stimulation to treat hypokinetic dysarthria in PD: A sham stimulation-controlled trial

    I. Rektorova, L. Brabenec, P. Klobusiakova, M. Kostalova (Brno, Czech Republic)

    Objective: To treat hypokinetic dysarthria (HD) in PD patients using multiple sessions repetitive transcranial magnetic stimulation (rTMS) Background: Based on results from our rTMS exploratory…
  • MDS Virtual Congress 2020

    Management of parkinsonian patients with long-term DBS and incomplete control of symptoms

    I. Reuter (Giessen, Germany)

    Objective: We want to evaluate if apomorphine infusions can improve symptom control in PD patients with long standing DBS and functional decline. Background: Deep brain stimulation…
  • MDS Virtual Congress 2020

    Effectiveness of dopaminergic drugs on motor symptoms in Parkinson’s disease patients with deep brain stimulation of subthalamic nucleus

    L.K SAHOO, D. Batra, N. Kamble, R. Yadav, D. S, P. Pal (Bangalore, India)

    Objective: To compare the effectiveness of dopaminergic drugs on motor symptoms assessed by UPDRS- III in Parkinson’s disease patients pre and post deep brain stimulation…
  • MDS Virtual Congress 2020

    Anticholinergic Burden in Parkinson’s Disease Patients in India – A Hospital Based Study

    A. Saini, R. Rajan, R. Anandapadmanabhan, V. Venogopalan, A. Gupta, B. Verma, N. Choudhary, R. Bhatia, M. Singh, A. Srivastava, P. Srivastava (New Delhi, India)

    Objective: To determine the cumulative anticholinergic burden in Indian Parkinson’s disease (PD) patients and to correlate the same with cognitive impairment and gait disturbance. Background:…
  • MDS Virtual Congress 2020

    Low dose Cabergoline for freezing of gait in advanced Parkinson’s disease – you can have your cake and eat it too!

    N. Sharma, A. Kumari, N. Sawal, H. Singh, K. Shukla (Chandigarh, India)

    Objective: To evaluate efficacy of cabergoline for treating FOG in advanced IPD. Background: FOG is a major cause of disability in advanced IPD. FOG responds…
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