Conjugal Parkinsonism
Objective: To report a case of multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) in a couple. Background: Conjugal parkinsonism denotes an entity where…Atypical Parkinsonism with LRRK2 Mutation Presenting as Multiple System Atrophy
Objective: We describe a rare case of atypical parkinsonism associated with leucine-rich repeat kinase 2 (LRRK2) gene mutation presenting with clinical features suggestive of multiple…A Randomized, Double-blind Phase 3 Trial of Amlenetug Versus Placebo in Patients with MSA: The MASCOT Trial
Objective: Describe the protocol for a randomized, double-blind phase 3 trial evaluating the efficacy and safety of amlenetug versus placebo in slowing clinical progression in…Dopa-Responsive Parkinsonism Secondary to Tauopathy: Clinical, Pathological, and Genetic Study
Objective: To report on the clinical, pathological, and genetic findings of four cases of levodopa-responsive parkinsonism with long survival and tauopathy. Background: The most common…Oxidative stress in Progressive Supranuclear Palsy
Objective: The goal of the study is to evaluate the significance of oxidative stress in the examination and pathophysiology of Progressive Supranuclear Palsy (PSP). Additionally,…Neurologic Music Therapy and Non-Invasive Brain Stimulation for Upper Extremity Performance in Patients with Corticobasal Syndrome
Objective: To explore the effects of Neurologic Music Therapy (NMT) with or without non-invasive brain stimulation on upper limb performance in patients with corticobasal syndrome…Simple linear measurements of the putamen reliably differentiate MSA from other parkinsonian disorders on MRI.
Objective: This study evaluates the utility of simple linear measurements of the putamen to distinguish Multiple System Atrophy (MSA) from idiopathic Parkinson’s Disease (iPD) and…Neuroprotective efficacy of EDTA against manganese neurotoxicity: Implications for modulating Parkinsonian syndromes
Objective: This study investigates the neuroprotective potential of ethylenediaminetetraacetic acid (EDTA) in reducing the neurotoxic effects of manganese (Mn), focusing on both motor and non-motor…Clinical and Dopaminergic Characteristics of MSA-C Patients with Predominant Cerebellar Asymmetry
Objective: To identify multiple system atrophy–cerebellar type (MSA-C) patients with marked cerebellar asymmetry and compare their features with symmetrically affected patients. Background: While asymmetry is…Normal Pressure Hydrocephalus in Vestibular Schwannoma Patients
Objective: The first objective is to evaluate the potential pathophysiological link between vestibular schwannoma (VS) and normal pressure hydrocephalus (NPH) by analyzing clinical features, imaging…
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