Distinct Gut Microbiome in Parkinson’s disease Based on the Presence of Premotor Rapid-Eye Movement Sleep Behavior Disorders: Exploring the Alpha-synuclein
Objective: We aim to investigate the microbiome composition and functional profiles in Parkinson’s disease (PD) patients with and without premotor rapid eye movement sleep behavior…Clinical features and brain [18F] FDG PET patterns in patients with progressive supranuclear palsy with and without ventricular dilatation
Objective: To describe the clinical features and the metabolic patterns assessed by the brain [18F] FDG-PET in a cohort of PSP patients with or without…Cortical activity during visually perturbed gait in older adults
Objective: The primary aim of this preliminary study was to explore pre-frontal cortex (PFC) and posterior parietal cortex (PPC) activity in older adults (OAs) during…Early GBA-Related Parkinson’s Disease has a Distinct Clinical Phenotype and Cholinergic Innervation
Objective: This study aims to characterize the clinical features and cholinergic innervation of early Parkinson’s disease (PD) patients with GBA mutations (GBA-PD). Background: The GBA-PD…Habenular Structural Connectivity Changes in Parkinson’s Disease: A 7T MRI Study
Objective: To assess if the structural connectivity of habenula (Hb) differs between Parkinson’s disease (PD) patients and healthy controls (HCs). Background: PD is marked by…Cerebral metabolic network in PLA2G6-associated parkinsonism
Objective: To characterize the cerebral metabolic network in PLA2G6-associated parkinsonism (PLA2G6-P). Background: PLA2G6-associated neurodegeneration is known as a continuum of phenotypes. Patients with late-onset PLA2G6-associated…Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder
Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…Characterization of a Novel alpha-synuclein PET radiotracer, [18F]C05-05, in a PPMI Sub-study
Objective: Characterization of the PET radiotracer, [18F]C05-05, in the PPMI Study Background: Validation of imaging biomarkers in Parkinson disease (PD) is a major objective of…Deep learning-based Prediction of Gait Dysfunction in Parkinson’s Disease using Quantitative Diffusion MRI from Brain Network Regions of Interest
Objective: Compare the performance of two deep learning models trained on quantitative diffusion measurements from brain network ROIs in the prediction of gait dysfunction in…Safety and efficacy of bilateral magnetic resonance-guided focused ultrasounds (FUS) thalamotomy for refractory essential tremor.
Objective: To describe the safety and efficacy of bilateral focused ultrasound thalamotomy (FUS) in a cohort of patients with essential tremor (ET) within the Spanish…
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