Impact of chronic LD treatment on metabolism, blood flow and blood-brain barrier permeability in the 6-OHDA rat model
Objective: To determine the effects of chronic LD treatment and induction of dyskinesias on cerebral metabolism, blood flow and blood-brain barrier permeability in 6-OHDA rat…Urate and homocysteine: Changes in motor and cognitive symptoms in newly diagnosed Parkinson’s disease
Objective: 1) To determine serum urate and homocysteine concentration at baseline, 18 and 36 months in control and PD participants. 2) To determine if urate…Impaired temporal coupling of action and perception in Parkinson’s disease
Objective: To study in Parkinson's disease (PD) the dependence of saccadic and perceptual reaction times (SRT and PRT) upon the temporal asynchrony (TA) between central…The impact of levodopa and apomorphine on beta- and gamma-oscillations in cortico-basal ganglia circuits in experimental parkinsonism
Objective: To clarify the role of pathologic oscillations in Parkinson's disease (PD) we recorded local field potentials (LFPs) in cortico-basal ganglia circuits of Parkinsonian and…Alterations in muscle synergies in early stage Parkinson’s disease
Objective: Identify whether muscle synergies are altered in stage I Parkinson's disease (PD). Background: Muscle synergies have been proposed as a mechanism utilized by the…Role of dopamine and GABA during subthalamic and pallidal deep brain stimulation: Evidence of dopamine release during subthalamic Deep Brain Stimulation
Objective: We recorded the single-unit activity of striatal cholinergic interneurons of healthy monkeys during high-frequency stimulation (HFS) of the subthalamic nucleus (STN) and globus pallidus…The evaluation of metabolic differences by using 18F-FDG-PET/CT in demented and non demented Idiophatic Parkinson’s disease patients
Objective: The objective of this study was to identify metabolic group differences between Idiopatic Parkinson's disease patients with dementia (PDD) and without dementia (PD), by…Subthalamic nucleus activity during virtual reality provoked lower limb freezing in a patient with Parkinson’s disease and freezing of gait
Objective: Record subthalamic nucleus activity in a Parkinson's disease patient with gait freezing while they perform a virtual reality walking task during DBS surgery. Background:…Apraxia in Parkinson’s disease
Objective: We aim to study apraxia in Parkinson's disease. Background: Limb apraxia is a cognitive motor disorder of skilled, purposive movements not caused by elementary…The small GTP-binding protein Rhes influences midbrain dopaminergic neurons: Behavioral and biochemical studies
Objective: Rhes is a small GTP-binding protein highly enriched in the striatum, developmentally regulated by thyroid hormone, and by dopamine (DA) innervation in adult rat…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.