MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Clinical features"

  • 2025 International Congress

    Clinical and Dopaminergic Characteristics of MSA-C Patients with Predominant Cerebellar Asymmetry

    DG. Park, YS. Kim, YS. An, JH. Yoon (Suwon, Republic of Korea)

    Objective: To identify multiple system atrophy–cerebellar type (MSA-C) patients with marked cerebellar asymmetry and compare their features with symmetrically affected patients. Background: While asymmetry is…
  • 2025 International Congress

    Differences Between Clinical and Imaging Phenotypes in Phase 2 Study of ATH434 in Multiple System Atrophy

    P. Trujillo, K. Hett, M. Bradbury, C. Wong, D. Stamler, D. Claassen (Nashville, USA)

    Objective: To assess differences between clinical and imaging phenotypes in Multiple System Atrophy (MSA) and evaluate the reliability of imaging biomarkers for subtype classification. Background:…
  • 2025 International Congress

    Functional Alterations in Early-Stage Parkinson’s Disease and Multiple System Atrophy with REM Sleep Behavior Disorder

    SC. Wang, Y. Xiao, YB. Hou, CY. Li, RW. Ou, JY. Lin, TM. Yang, NN. Che, QR. Jiang, XT. Zheng, JY. Liu, HF. Shang (Chengdu, Sichuan, China)

    Objective: This study investigated functional brain network alterations in early-stage Parkinson’s disease (PD) and multiple system atrophy (MSA) patients with probable rapid eye movement sleep…
  • 2025 International Congress

    Brain perfusion patterns associated with motor symptoms in multiple system atrophy

    Y. Nakano, A. Sugiyama, S. Hirano, Y. Nakagawa, M. Tamura, T. Yamamoto, Y. Koizumi, Y. Suzuki, K. Yamagishi, Y. Chishiki, S. Kuwabara, Y. Kitayama (Chiba, Japan)

    Objective: There is a need for objective methods to assess disease progression in multiple system atrophy (MSA). This study aimed to identify brain perfusion patterns…
  • 2025 International Congress

    The Role of FGF14 GAA Repeat Expansions in Multiple System Atrophy: Frequency, Phenotypic Correlations, and Prognostic Implications

    V. Chelban, D. Pellerin, N. Vijiaratnam, S. Sambin, M. Ostrozovicova, C. Girges, P. Leigh, L. Beichert, C. Bonnet, M. Renaud, W. Meissner, A. Sieben, D. Crosiers, P. Cras, S. Zuchner, J-C. Corvol, M. Farrer, M. Synofzik, B. Brais, T. Warner, H. Morris, Z. Jaunmuktane, T. Foltynie, H. Houlden (London, United Kingdom)

    Objective: This study aimed to investigate the frequency of FGF14 GAA•TTC repeat expansion in clinically diagnosed and pathologically confirmed multiple system atrophy cases. Background: Partial…
  • 2025 International Congress

    Retrospective analysis of MSA diagnosis in a neuroscience hospital

    M. Wazil, M. Farhan Abdulla, J. Mitchell, D. Damodaran (Liverpool, United Kingdom)

    Objective: We evaluated the extent to which diagnoses of MSA align with the MDS criteria within a specialist neurology trust in the UK. We aimed…
  • 2025 International Congress

    Novel Multiple System Atrophy Subtypes Identified Using Unsupervised Machine Learning Algorithms

    H. Sekiya, D. Ono, A. Maier, D. Dickson (Jacksonville, USA)

    Objective: To identify a novel disease subtype of multiple system atrophy (MSA) by applying machine learning algorithms to a large cohort of autopsy-confirmed MSA. Background:…
  • 2024 International Congress

    Optical Coherence Tomography Findings in Multiple System Atrophy: Insights into Disease Subtypes, Clinical Correlations, and Dopaminergic Degeneration

    Y. Kang (Hangzhou, China)

    Objective: This study aimed to evaluate optical coherence tomography (OCT) findings in multiple system atrophy (MSA) patients, with a focus on disease subtypes, clinical correlations,…
  • 2024 International Congress

    Characteristics of Language Abnormalities in Multiple System Atrophy and Parkinson’s Disease

    M. Subert, M. Novotny, P. Dusek, J. Klempir, J. Rusz, T. Tykalova (Prague, Czech Republic)

    Objective: We characterized complex language profile and explore diagnostic potential of automated language analysis of natural spontaneous speech in differentiation between multiple system atrophy (MSA)…
  • 2024 International Congress

    Lyme disease presenting as a rapidly progressive MSA-C look alike

    L. Zünd-Hofer, F. Brugger (Sankt Gallen, Switzerland)

    Objective: We report two cases of encephalomyelitis due to Lyme disease with cerebellar ataxia and autonomic symptoms, which presented with a rapidly progressive MSA-like phenotype.…
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