MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Treatment"

  • 2023 International Congress

    UMSARS versus laryngoscopy-based assessment of dysphagia

    N. El Fassi, A. Pavy-Le-Traon, E. Mouchon, O. Rascol, W. Meissner, A. Foubert-Saumier, Y. Gallois, S. Tessier, F. Ory-Magne, V. Woizard, M. Fabbri (Toulouse, France)

    Objective: To compare the Unified Multiple System Atrophy Rating Scale (UMSARS)   part I-item 2 with an ear/nose/throat (ENT) expert physician assessment. Background: Early and severe…
  • 2023 International Congress

    Identifying a path to improve diagnostic delay and access to care for PSP, CBS, and MSA

    M. Bruno, F. Ali, M. Dale, M. Schmidt, M. Comeau, C. Spears, J. Shurer (Honolulu, USA)

    Objective: To understand diagnosis and care experiences of patients and care partners living with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy…
  • 2023 International Congress

    Analysis of the therapeutic potential of c-Abl inhibition in Multiple System Atrophy

    M. Werner, E. Bertin, A. Simmonet, E. Noé, P. Fernagut, J. Molina, K. Lowe, E. Bezard, J. Kordower (Atlanta, USA)

    Objective: IkT-148009 is a potent selective inhibitor of non-receptor Abelson Tyrosine Kinases (c-Abl kinases).  Our recent analysis of post-mortem brain tissue from patients with Multiple…
  • 2023 International Congress

    Baseline characteristics for patients with multiple system atrophy entering a randomized, controlled study of the anti-α-synuclein monoclonal antibody Lu AF82422

    W. Singer, A. Takeda, L. Kjærsgaard, J. Wiedemann, A. Berger, A. Varrone, A. Bidani, D. Meulien (Rochester, USA)

    Objective: Report baseline characteristics for patients with multiple system atrophy (MSA) entering a study to assess the safety and efficacy of alpha-synuclein (α-syn) monoclonal antibody…
  • 2023 International Congress

    A multiple-dose thorough QT study to evaluate the effect of ampreloxetine on cardiac repolarization in healthy subjects

    M. Borin, J. Kanodia, R. Graham, A. Lo, B. Zheng, D. Bourdet (South San Francisco, USA)

    Objective: To characterize the effect of therapeutic and supratherapeutic doses of ampreloxetine on cardiac repolarization in healthy subjects. Background: Ampreloxetine is a potent NE reuptake…
  • 2022 International Congress

    Safety and Efficacy of Verdiperstat, a Novel Myeloperoxidase Inhibitor, in MSA

    I. Qureshi, V. Wirtz, L. Brady, J. Ellison, A. Ellenbogen, R. Freeman, G. Höglinger, H. Kaufmann, A. Lang, P. Low, W. Meissner, P. Millar Vernetti, H. Morris, J. Palma, S. Perlman, W. Poewe, J. Schmahmann, K. Seppi, W. Singer, S. Vernino, G. Wenning (New Haven, USA)

    Objective: To present results from M-STAR, a phase 3, randomized controlled trial evaluating the disease modifying effect of verdiperstat in participants with MSA. Background: MSA…
  • 2022 International Congress

    Focused ultrasound offers tremor relief in multiple system atrophy patients

    M. Nassar, A. Sinai, L. Shornikov, I. Erikh, M. Constantinescu, M. Zaaroor, I. Schlesinger (Haifa, Israel)

    Objective: To report on the efficacy and safety of MRI-guided focused ultrasound (FUS) VIM-thalamotomy in patients with multiple system atrophy (MSA). Background: FUS has established…
  • 2022 International Congress

    The shaky truth of a Movement Disorder Nurse pilot program in Rural Australia

    L. Bellizzi (Horsham, Australia)

    Objective: The conception of the Movement Disorder Nurse program began when the Australian Government and Fight Parkinson’s conducted a scoping evaluation of people living with…
  • 2022 International Congress

    It takes a village: An interdisciplinary care model for atypical Parkinsonism

    H. Glover, J. Shurer, M. Ivancic, M. Sklerov (Chapel Hill, USA)

    Objective: To describe one interdisciplinary clinic designed to offer comprehensive care to patients with atypical parkinsonism syndromes, and to share the lessons learned which may…
  • MDS Virtual Congress 2021

    Cerebellar tDCS for multiple system atrophy cerebellar: Double blinded, randomized, sham-control, cross-over study

    JH. Ahn, J. Song, I. Choi, DY. Lee, JW. Cho, WH. Chang, J. Youn (Seoul, Republic of Korea)

    Objective: The aim of study is to investigate an effect of a transcranial direct current stimulation (tDCS) on the primary motor cortex (M1) and cerebellum…
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