From Subclinical Symptoms to Post-Surgical Challenges: A Pediatric Case of Craniopharyngioma
Objective: To provide a case of subclinical symptoms including motor tics in a child found to have a large craniopharyngioma with post surgical parkinsonism. Background:…Novel Genetic Variant Associated with Parkinsonism
Objective: Case presentation of a novel genetic variant associated with parkinsonism. Background: Parkinsonism is a clinical syndrome characterized by a combination of bradykinesia, rigidity, tremor…Juvenile parkinsonism masquerading as hereditary spastic paraplegia
Objective: To present a patient with juvenile parkinsonism initially presented with billateral foot dystonia and inreased deep tendon reflexes. Background: Patients with juvenile parkinsonism may…Impact of manganese exposure on neurobehavioral disorders in rats: Insights into oxidative stress pathways and Parkinsonian syndrome pathophysiology
Objective: This study investigates the correlation between oxidative stress in various neural structures induced by manganese (Mn) and the onset of anxious and depressive behaviours…Quantitative evaluation of speech characteristics in Assessment of Motor Speech for Dysarthria (AMSD) using acoustic analysis
Objective: This study aims to extract acoustic features from speech data obtained from patients undergoing the Assessment of Motor Speech for Dysarthria (AMSD), a clinical…Promising Remote Markers of Motor Progression in Isolated REM Sleep Behaviour Disorder
Objective: To define the motor progression of motor prodromes using two remote keyboard tapping tests (BRAIN and DFT tests) and two remote standardised clinical rating…L1CAM and TMEM119 enriched Exosomal markers in Parkinson’s Disease and Progressive Supranuclear Palsy: A Prospective Study
Objective: This study explored longitudinal changes in cellular inflammatory, autophagic mediators in L1CAM and TMEM119-enriched exosomal samples of patients with Parkinson’s disease (PD) and Progressive…Accuracy of the Tanner’s Questionnaire and the REM Sleep Behavior Disorder Single-Question Screen as Screening Tools for Parkinson’s Disease in a Brazilian Cohort
Objective: Assess the Tanner’s Questionnaire (TQ) and the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q) performance as screening tools for Parkinson’s Disease (PD) in a…Differentiating Parkinsonism and related diseases by specific Parkinsonism patterns
Objective: This study aimed to identify characteristic parkinsonism patterns across PD, MSA and PSP, and evaluate their utility in early differentiation. Background: Parkinson's disease (PD), multiple…Evaluation of Nociception in a Model of Parkinson’s Disease for the Study of Non-Motor Symptoms in Trpv4-/- Animals
Objective: This study aimed to investigate the role of the TRPV4 receptor in regulating the nociception in a PD model experimental for the study of…
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