Visual Hallucinations and Pareidolias Across the Lewy Body Disease Spectrum
Objective: To systemically evaluate visual hallucinations and illusions in patients across the LBD spectrum and to discover the underlying neural mechanism behind these visual symptoms.…Handwriting Features in Patients with Isolated REM Sleep Behaviour Disorder
Objective: To assess iRBD patients’ handwriting features and develop a rating scale capable of detecting early hallmarks of disease. Background: Handwriting changes, such as micrographia,…A UK-wide Effort for Identification of Loci for Autosomal Dominant Parkinson’s Disease
Objective: (i) To describe the demographic, clinical and genetic features of a large cohort of familial autosomal dominant Parkinson’s disease (PD) patients in the UK.(ii)…The Inhibition of Mitochondrial NLRP3 Inflammasome Decreases Dopaminergic Cell Death in a 6-OHDA Mouse Model of Parkinson’s Disease.
Objective: To evaluate the possible neuroprotective effects of mitochondrial NLRP3 inflammasome inhibition in a 6-hydroxydopamine mouse model of Parkinson's Disease. Background: Overactivation of brain immune…Wilson’s Disease About A Complex Case
Objective: We report the case of a patient who experienced diagnostic wavering. Background: Wilson disease is a rare disease. Cases in Africa is even rarer.…Plasma MicroRNA Expression Profiling in patients with Multiple System Atrophy and Parkinson’s Disease
Objective: Our objective was to identify differentially expressed, circulating miRNAs in Multiple System Atrophy-Parkinsonian type (MSA-P) and Parkinson’s disease (PD) which could serve as diagnostic…Mild Behavioral Impairment in Lewy body disease: a potential marker of phenoconversion and disease severity
Objective: To explore the association between mild behavioral impairment (MBI) and disease severity in a predefined prospective cohort with Lewy body disease (LBD) spectrum Background:…Real-world use of biomarkers for Parkinsonism: Should I do this (pSyn) or DaT?
Objective: To examine the utility of commercially available skin phosphorylated alpha-synuclein deposition test (pSyn) in patients with clinically ambiguous parkinsonism and its concordance with dopamine…Parkinsonism in setting of hypoparathyroidism
Objective: There may be overlap between symptoms of hypoparathyroidism such as tremor and bradykinesia and Parkinsonism. Recognizing this possibility allows for appropriate clinical management. Background:…Association between Parkinsonism, Parkinson’s Disease and Cognitive Impairment and Incidence of Dementia in People with Parkinsonism and Parkinson’s Disease in Latin America: A 10/66 Dementia Research Group Study
Objective: The study aimed to determine the cross-sectional and prospective associations between parkinsonism and Parkinson's disease with cognitive impairment and dementia in a large multi-country…
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