Association Between Motor Symptoms and Autonomic Dysfunction in De Novo Parkinson’s Disease: Insights into the Role of the Gut-Brain Axis
Objective: This retrospective study aimed to investigate the relationship between motor symptoms and autonomic dysfunction in patients with de novo Parkinson's disease(PD). Background: Dysautonomia in…Patient-developed Unique Methods to Overcome Freezing of Gait in Parkinsonian Disorders
Objective: To present and share unique methods to overcome freezing of gait (FOG) in parkinsonian disorders. Background: Freezing of gait (FOG) is an episodic and…The Impact of VPS35 D620N Mutation on Alternative Autophagy and its Reversal by Estrogen in Parkinson’s Disease
Objective: We investigated the relationship between alternative autophagy and VPS35 D620N mutant-related PD pathogenesis. Background: VPS35 is critically involved in the mechanisms of neurodegeneration observed…Prolonged Positive Response: Subthalamic Nucleus as a Deep Brain Stimulation Target in X-linked Dystonia-Parkinsonism
Objective: To demonstrate long-term improvement of parkinsonism and dystonia in patients with X-linked dystonia-parkinsonism (XDP) following deep brain stimulation (DBS) in the subthalamic nucleus (STN).…Prevalence of Parkinson’s Disease and Possible Parkinsonian Syndrome in Gaucher Disease: Data From the ICGG Gaucher Registry
Objective: To estimate the age-specific risk of Parkinson’s disease (PD) and possible parkinsonian syndrome (pPS) in Gaucher disease (GD) based on registry data. Background: While…7year followup of Asia’s first case of sporadic ATP6AP2 Mutation: α-synucleinopathy or tauopathy?
Objective: ATP6AP2 mutation, previously described in literature to cause early onset Parkinson’s disease (PD) with atypical signs, evolved into frontotemporal lobar degeneration in a 7year…Movement disorders in patients with central nervous system tuberculosis: A systematic review
Objective: We conducted a critical review of the literature on movement disorders (MD) in patients with central nervous (CNS) tuberculosis (TB), with the goal of…Multiple System Atrophy in a Patient with Normal Pressure Hydrocephalus
Objective: To review a case of a patient diagnosed with both NPH and MSA. Background: Multiple system atrophy (MSA) is a progressive neurodegenerative disease that…Parkinson’s disease in a Special Population -Diagnosis and treatment of Parkinson’s disease in cases of psychiatric disorders treated with dopamine receptors antagonists-
Objective: We studied diagnosis and treatment of Parkinson’s disease in cases of psychiatric disorders treated with dopamine receptors antagonists for a long time. Background: Schizophrenia…Identifying key symptoms associated to parkinsonism other than Parkinson’s Disease: a case series
Objective: This study aims to identify the main symptoms associated with the clinical diagnosis of parkinsonism, excluding Parkinson's disease (PD), among patients evaluated by non-specialist…
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