Gait Analysis in Parkinson’s Disease with Mixed Reality
Objective: This study aims to analyze gait differences between individuals with Parkinson’s disease (PD) and healthy participants using the Timed Up-and-Go (TUG) test, exploring the…Digital Health Interventions for Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Objective: To assess the effectiveness of digital health interventions (DHIs) in patients with Parkinson's disease (PD) and report on their reach, uptake, and feasibility. Background:…The MJFF PRKN/PINK1 Project
Objective: To i) establish an expert consortium on PRKN/PINK1-linked Parkinson’s disease (PD), ii) improve our understanding of genotype-phenotype relationships and disease mechanisms, and iii) establish…Transcranial direct current stimulation combined with motor training for motor symptoms in Parkinson’s disease: a systematic review and meta-analysis
Objective: We aimed to compare the acute and retention effects of motor training alone versus its combination with transcranial direct current stimulation (tDCS) on motor…Results From a Dose-Blinded, Phase II Extension Study Evaluating Long-Term Efficacy, Safety and Tolerability of Minzasolmin in Participants With Parkinson’s Disease
Objective: ORCHESTRA XT (PD0055; NCT05543252) was a Phase II, dose-blinded extension of the ORCHESTRA Phase II, proof-of-concept study (NCT04658186). ORCHESTRA XT assessed the pharmacodynamic effects of…Efficacy of Combined Transcranial Direct Current Stimulation (tDCS) and Gait Training on Gait in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Objective: To evaluate the effects of addition of tDCS to gait training on gait parameters and motor function in individuals with Parkinson’s disease Background: Gait…Physiological assessment of swallowing related muscles in patients with Parkinson’s disease: characteristics and utility of high-density surface electromyography
Objective: The study focused on high-density surface electromyography (HD-sEMG) as a novel method to understand the electrophysiological characteristics of swallowing-related muscles in patients with Parkinson's…Improvement of Freezing of Gait with Personalized Rhythmic Auditory Stimulation in Parkinson’s Disease
Objective: To determine if different types of personalized music rhythmic auditory stimulation (RAS) training can improve gait control in Parkinson's Disease (PD) patients with freezing…Establishing and Leveraging a Community Advisory Board to Guide Study Design, Speed Recruitment and Encourage Retention
Objective: To describe the formation and impact of the Parkinson’s Progression Markers Initiative (PPMI) Community Advisory Board (CAB). Background: Community advisory boards are critical partners…Impact of Allogeneic Mesenchymal Stem Cells in Motor and Non-Motor Symptoms of Parkinson’s Disease: A Phase 2 Randomized Trial
Objective: To assess the efficacy of repeated intravenous (IV) allogeneic bone marrow-derived mesenchymal stem cell (allo-hMSC) infusions in reducing motor and non-motor symptoms in people…
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