Identification of Pre-Diagnostic Biomarkers for Parkinson’s Disease from Plasma Proteome
Objective: To identify pre-diagnostic biomarkers for Parkinson’s Disease (PD) from the plasma proteome. Background: The plasma proteome is a non-invasive and accessible measure to assess…Mitochondrial Complex I Brain Imaging in Parkinson’s Disease and Lewy Body Dementia
Objective: To compare brain mitochondrial respiratory Complex-1 (mito-C1) between Parkinson’s disease (PD) and PD dementia/Dementia with Lewy Bodies (PDD/DLB) participants and unimpaired controls, using 18F-BCPP-EF,…Motion-robust high-resolution imaging of nigrosome-1 in Parkinson’s disease
Objective: To develop a motion-insensitive high-resolution susceptibility weighted imaging (SWI) sequence for evaluating nigrosome-1 in substantia nigra. Background: In Parkinson's disease (PD) increased amounts of…Classification of Parkinson’s disease using AI based on multi-modal brain MRI connectomics
Objective: To develop a novel artificial intelligence (AI) model using connectivity matrices derived from multi-modal brain magnetic resonance imaging (MRI) to aid diagnosis and subtyping…Inflammation Biomarkers and Free Water Fraction in the Cholinergic Forebrain System in Idiopathic Parkinson’s Disease
Objective: Investigate if inflammatory biomarkers moderate the association between, cholinergic basal forebrain free water fraction and cholinergic innervation in idiopathic Parkinson’s disease. Background: The cholinergic…Frontal Lobe Cortical Thickness and Volumetric Analysis in Parkinson’s Disease Based on Impulse Control Disorder
Objective: Characterize differences in frontal cortical thickness and volumes in Parkinson’s disease based on impulse control disorder. Background: Impulse control disorder (ICD) is a debilitating…Evoked Resonant Neural Activity Automates Field Shaping of Subthalamic Nucleus-Deep Brain Stimulation in Parkinson’s Disease
Objective: Compare motor efficacy and tolerability of 3 methods to guide electrical field shaping of subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinsons disease…Unilateral MRgFUS subthalamotomy in Parkinson’s disease: A prospective clinical study
Objective: To study the efficacy and safety of this treatment in a similar cohort of patients and to characterize the lesions. Background: Unilateral subthalamic nucleus…Telemonitoring-assisted DBS Optimization For Parkinson’s Disease Patients
Objective: This is a case report of Parkinson's disease (PD) patients who underwent deep brain stimulation (DBS) surgery and were remotely monitored using a validated…Deep Brain Stimulation during pregnancy: A systematic review of the literature
Objective: We conducted a critical appraisal of the literature on pregnant patients using deep brain stimulation (DBS) in order to assess safety outcomes for maternal…
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