The frequency of glucocerebrosidase mutations in a subgroup of early-onset Parkinson’s disease patients in the Korean population
Objective: We investigated the frequency of GBA mutations in the Korean patients with early-onset Parkinson’s disease (PD). Background: Glucocerebrosidase (GBA) mutations are associated with increased…Motor resonance flexibility to emotion-enriched context in Parkinson’s disease patients with and without freezing of gait.
Objective: This study aims at exploring the response of the mirror neuron system, specifically motor resonance, to an emotion-enriched context in people with Parkinson disease…Characterization of gastrointestinal dysfunction in Parkinson’s by disease stage
Objective: To conduct a comprehensive cross-sectional and longitudinal characterization of gastrointestinal dysfunction (GID) in Parkinson’s disease (PD). Background: GID is an important feature of PD…Can we add whey protein supplementation in patients with Parkinson’s disease without interfering with levodopa response?
Objective: The main endpoint of the study was to evaluate if a daily intake of whey protein-based dietary supplement causes a worse response to levodopa…Scaling the Roche Digital Health Technology Platform to Assess Disease Severity and Progression in Individuals with Parkinson’s Disease
Objective: Here we present the development of a novel platform to deliver the Roche Parkinson’s Disease (PD) Mobile Application to researchers to actively measure motor…Boostering motor imagery processing to improve gait in patients with Parkinson disease and freezing of gait: a preliminary study
Objective: The aim of this study is to evaluate the priming effect of visual, auditory and cognitive tasks in enhancing Motor Imagery (MI) ability in…Performance of oral diadochokinesis in Parkinson’s Disease motor subtypes
Objective: To compare the performance of the oral diadochokinesis task in the different motor subtypes of PD (postural instability/gait difficulty - PIGD, tremor-dominant - TD,…Pilot study to investigate the use of in-clinic sensing to identify optimal stimulation parameters for deep brain stimulation therapy in Parkinson’s disease
Objective: Compare the use of in-clinic sensing functionality and standard of care monopolar review for identifying optimal settings of a deep brain stimulation (DBS) in…Parkin deficiency impairs mtDNA dynamics and propagates inflammation
Objective: We sought to explore Parkin’s role in (i) averting neuronal mtDNA dyshomeostasis/release and (ii) the activation of downstream inflammatory processes. Background: Mutations in Parkin…Challenges in Outcome Measure Selection in Multi-Arm Multi-Stage Clinical Trials in Parkinson Disease
Objective: The Edmond J Safra Accelerating Clinical Trials in Parkinson Disease (PD) initiative (EJS ACT-PD) aims to accelerate the identification of disease modifying treatment for…
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