Inducing motor cortical plasticity in Parkinson’s Disease patients using subthalamic deep brain stimulation and repetitive transcranial magnetic stimulation
Objective: To investigate whether motor cortical plasticity can be induced in Parkinson’s disease (PD) patients by pairing subthalamic deep brain stimulation (STN-DBS) and repetitive transcranial…Clinical phenotype of non-manifesting carriers of mutations in the GBA and LRRK2 genes
Objective: To explore the influence of carrying mutations in both the GBA and LRRK2 genes (dual mutation carriers) on risk for future development of Parkinson's…Outcomes after Deep Brain Stimulation (DBS) surgery in patients with young-onset Parkinson’s disease
Objective: To assess outcomes after deep brain stimulation (DBS) in patient with young-onset Parkinson’s disease (PD). Background: DBS is a surgical procedure which effectively treats…Blood biomarkers and their association with non-motor symptoms in early Parkinson’s Disease
Objective: To identify if baseline blood biomarkers are associated with non-motor symptoms in early PD. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with…Long-term safety of continuous levodopa/carbidopa infusion with ND0612: Data from patients who continued past one year in the BeyoND study
Objective: To report long-term safety and tolerability data from the ongoing BeyoND study (NCT02726386) for patients who continued treatment past the one-year primary endpoint. Background:…Comparison of Disease Progression in Patients with Brain-first versus Body-first Parkinson’s Disease
Objective: This study aimed to compare the clinical progression between brain-first and body-first PD groups using cardiac sympathetic denervation (CSD). Background: Brain-first and body-first Parkinson’s…Preferences for discussing sexual health concerns
Objective: To investigate the sexual needs of PwP, and understand their preferences for discussing sexual health concerns.To propose an intervention framework tailored for PwP in…LRRK2 and GBA major variants in the New York Mount Sinai BioMe Biobank
Objective: To characterize the frequency of major LRRK2 and GBA variants in a multi-ethnic New York cohort with and without Parkinson disease (PD). Background: There…Quality of Life and Motor Outcomes for Parkinson’s Disease Patients 12 Months After Deep Brain Stimulation in China
Objective: Demonstrate improvement in Parkinson’s disease (PD)-related quality of life (QoL) for Deep Brain Stimulation (DBS) patients in a prospective, multicenter study conducted in China.…History of Comorbidities and their Association with Developing Cognitive Dysfunction in PD
Objective: To examine comorbidities associated with incident cognitive dysfunction in PD. Background: The risk of dementia is up to six-times higher in PD compared to…
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