Tendencies of Non-Motor Symptoms and Short-Term Clinical Predictors in Patients with Parkinson’s Disease
Objective: This study retrospectively investigated whether the occurrence of non-motor symptoms and the decline in cognitive function in patients with Parkinson’s disease (PD) influence fall…Investigating the role of NLRP3 Inflammasome as Biomarkers and Therapeutic Targets in Parkinson’s Disease Pathogenesis
Objective: To elucidate the role of NLRP3 Inflammasome in PD pathogenesis and its role in differential susceptibility. Background: Inflammasomes play a role in the progression…The Bjorn Moller Research Repository: A Resource for Movement Disorders Research
Objective: To build a repository of longitudinally collected biological samples and clinical, demographic, and lifestyle data from individuals with Parkinson’s disease (PD) and other movement…Utilising Beta Power in Local Networks to Predict Freezing of Gait Events in Parkinson’s Disease
Objective: Our study examined brain network changes during the transition to Freezing of Gait (FOG) versus voluntary stopping. Identifying specific neural alterations may help establish…TMS-EEG Provides Objective Neurophysiological Measures of Motor Fluctuations in Parkinson’s Disease
Objective: To assess the correlates TMS evoked potentials (TEPs) measurements changes representing interhemispheric transmission to the change in motor symptoms in 'off' versus 'on' states.…Combining Pharmaceutical and Digital Treatment Approaches in Parkinson’s Disease Modulates of the Limbic System, Supporting Emotional Regulation and Motivated Behaviors
Objective: Following the combination of standard levodopa treatment with a digital intervention in Parkinson's disease (PD), we assessed the associations between neuroplasticity within the limbic…Gray Matter Microstructural Integrity in Relation to Frontostriatal and Posterior Cortical Cognitive Performance in Parkinson’s Disease
Objective: Explore relationships of frontostriatal (FS) and posterior cortical (PC) cognitive performance with gray matter (GM) microstructural integrity in Parkinson’s disease (PD). Background: The dual…LRRK2 Polymorphisms and Associations with Parkinson’s Disease in Participants of East Asian, Southeast Asian, and European Descent
Objective: To investigate the prevalence of LRRK2 polymorphisms, R1628P and G2019S, and their association with Parkinson’s Disease (PD) in cohorts of East Asian (EA), Southeast…Rare Variant Analysis of Sphingolipid-related Genes in Large Chinese Parkinson’ s Disease Cohorts
Objective: This study investigated the link between rare variants in sphingolipid-related genes and Parkinson’s disease (PD) in a Chinese mainland population. Background: Recently, growing evidence…Longitudinal Analysis of Disease Progression in GBA-Associated Early-Onset Parkinson’s Disease
Objective: This study aims to investigate the longitudinal disease progression of early-onset Parkinson’s disease (EOPD) in carriers of GBA mutations compared to genetically undefined EOPD…
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