Bayesian Re-Analysis of Phase I and II Subthalamic Nucleus Perfusion Changes Following Mesenchymal Stem Cell Infusion in Parkinson’s Disease
Objective: To compare subthalamic nucleus (STN) perfusion changes following mesenchymal stem cell (MSC) infusion in Parkinson’s disease (PD) using Bayesian methods in both Phase I…Impact of Patient-Specific Structural Connectivity of STN-DBS on Balance and Mobility – Pilot study
Objective: To evaluate the impact of patient-specific structural connectivity between VTA in STN targeting and SMA/preSMA on functional mobility improvements in PD patients undergoing DBS.…The Genetic Landscape of Parkinson’s Disease in African and Admixed Populations: Discovering Population-Specific Risk and Unveiling Etiological Insights
Objective: To perform the largest PD risk genome-wide association study (GWAS) in the African and African admixed populations. Background: Investigating the genetic foundation of Parkinson’s…First Insights into Genetic Findings from the Mexican Parkinson’s Research Network (MEX-PD): The Case of MTHFR
Objective: To present the first genetic findings of the MEX-PD cohort, with a specific focus on analyzing the role of MTHFR variants Background: Despite significant…Parkinson’s disease (PD) associated with the E46K mutation in the SNCA gene, twenty years after
Objective: To provide an updated overview of Parkinson’s disease (PD) associated with E46K mutation carriers in the SNCA gene 20 years after its description, incorporating…A Case for Novel Phenotypes Associated with Digenic CHMP2B-LRRK2 Mutations
Objective: We report a patient presenting with both bv-FTD & PD phenotypes, alongside a complex family history featuring multiple neurodegenerative disorders. Background: The CHMP2B &…Building Genetic Counseling Capacity in Latin America: The PD GENEration–LARGE-PD Training Framework
Objective: The PD GENEration (PD GENE) study has expanded into Latin America through collaboration with the Latin American Research Consortium on the GEnetics of Parkinson's…Automated Image-Guided Programming Algorithm Supports Clinicians During DBS Programming for Parkinson’s Disease Patients
Objective: To assess clinical outcomes of an acute automated image-guided programming (aIGP) algorithm in PD patients implanted with a deep brain stimulation (DBS) system. Background:…Optimization of Adaptive Deep Brain Stimulation Settings in Patients with Parkinson’s Disease
Objective: To evaluate the specific programming parameters of adaptive deep brain stimulation (aDBS) in Parkinson’s disease (PD) and identify the most effective settings for optimizing…Deep Brain Stimulation in Late-Stage Parkinson’s Disease: Insights from Clinical Practice
Objective: To compare Late-stage Parkinson's disease (LSPD) patients who completed at least one year of oral medical therapy alone after IPG depletion with those who…
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