Comparison of Microglial PET Imaging in Parkinson’s Disease, RBD, and Controls with a CSF1R and TSPO Ligand.
Objective: To compare regional binding patterns of microglial PET radioligands: [11C]DPA-713, a TSPO ligand, and [11C]CPPC1, a CSF1R ligand in people with Parkinson’s disease (PD).…Cerebello-Thalamo-Cortical Tract Microstructural Changes in Parkinson’s Disease Patients with Tremor
Objective: To evaluate microstructural characteristics in the cerebello-thalamo-cortical circuit (CTC) of Parkinson's Disease (PD) patients with different tremor phenotypes. Background: Tremor is one of the…Description Genotype/phenotype of patients with Parkinson’s disease. Report of an Argentinean cohort included in the LARGE PD Consortium.
Objective: To characterize the genetic and phenotypic profile of Argentinean Parkinson's patients and contribute to the understanding of the genetic heterogeneity of this disease. Background:…Investigating the Global Genetic Spectrum of Monogenic Parkinson’s Disease and Parkinsonism
Objective: To investigate known pathogenic and risk variants linked to Parkinson’s disease (PD) at a global, multi-ancestry scale. Background: Genetic forms of PD have been…Non-motor Symptoms, Sleep Disturbances, And Genetic Insights In Young Onset Parkinson’s Disease: A Prospective Descriptive Study
Objective: 1. To study the prevalence of various non-motor symptoms in Young onset Parkinson's Disease patients2. To study the genetic markers in YOPD patients. Background:…Clinical Differences Among Parkinson’s Disease Patients Carrying GBA1 Variants in Colombia: Insights From LARGE-PD Consortium
Objective: To compare the clinical manifestations of GBA1 variants p.K198E, p.E326K, and p.N370S in Parkinson’s disease(PD) patients in Colombia. Background: GBA1 variants have been identified…Assessing Individual Risk Through Determination of Local Ancestry: Insights from the Global Parkinson’s Genetics Program
Objective: We're developing a scalable pipeline to infer local ancestry (LA) for individuals in the Global Parkinson's Genetics Program (GP2). This approach aims to enhance…Screening for GBA1 p.K198E PD-Risk Variant in Latin America
Objective: We aimed to assess the distribution of the GBA1 p.K198E variant, linked to Gaucher’s disease (GD) and increased Parkinson’s disease (PD) risk, across Latin…DBS Programming in Early Simultaneous STN-GPi Implantation for Young-Onset Parkinson’s: A Mini Case Series
Objective: We aim to present our institution's experience with simultaneous dual STN-GPi implantation in Parkinson’s disease (PD) by analyzing a case series of 3 patients.…Impact of Insurance and Risk Factors on DBS Outcomes
Objective: Assess the effect of insurance type on deep brain stimulation (DBS) outcomes, and identify risk factors for progression to assisted ambulation and dependency (home…
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