Longitudinal Change of Substantia Nigra Hyperechogenicity in Parkinson’s Disease Cohort
Objective: To analyze whether the size of SN+ is differentially affected depending on disease duration. Secondly to analyze the interaction between a range of clinical…Targeted deep sequencing of brain DNA for detection of somatic point mutations in synucleinopathies
Objective: To detect relevant somatic "point mutations" (single nucleotide variants- SNVs) in brain-derived DNA in synucleinopathies. Background: There is increasing recognition that neurons may harbour…Sequencing of single human nigral dopaminergic neurons for somatic copy number variants
Objective: To detect somatic DNA copy number variants (CNVs) in dopaminergic neurons isolated from human substantia nigra, using shallow whole genome sequencing (WGS). Background: Somatic…The trace of substantia nigra hyperechogenicity: a clinical observation
Objective: To present an empirical observation regarding transcranial ultrasound in movement disorders and scalp sebum smear. Background: Transcranial ultrasound (TUS) detects substantia nigra hyperechogenicity (SN+) in…Transcranial ultrasound in atypical parkinsonism: how reliable is it in real clinical practice? A multi-centre comprehensive study
Objective: To assess real clinical practice usefulness of transcranial ultrasound in atypical parkinsonism differential diagnosis, and to perform a critical analysis of previous literature in…Substantia Nigra Hyperechogenicity in Parkinson’s Disease and Essential Tremor and its Association with Premotor Symptoms of Parkinson’s Disease
Objective: To compare the frequency of Substantia Nigra hyperechogenicity (SN+) in patients with essential tremor (ET) and Parkinson’s disease (PD), to determine the frequency of…Could curcumin be the preventive key of parkinson’s disease?
Objective: The present study evaluates the possible protective effect of curcumin on rats exposed to aluminum which is a major risk factor of parkinson's disease.…The effects of STN-DBS on the Parkinson’s disease patients with different progressive rates
Objective: The aim of this study is to explore the effects of STN-DBS on the Parkinson's disease patients with different progressive rates Background: Studies indicate…Clinical spectrum of vascular Parkinsonism: A hospital-based study in south India
Objective: to Study the profile of akinetic rigid syndromes with special reference to Vascular Parkinsonism Background: Parkinson disease (PD) is a primary neurodegenerative disease but…Prevalence of Autonomic dysfunction and its correlation with Clinico-imageological features in Parkinson’s Disease
Objective: To study the prevalence of autonomic dysfunction and to correlate with clinico-imageological features and to assess the impact of autonomic dysfunction on quality of…
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