Brain De-Ironization with Nasal Spray of Iron Chelator in Treatment of Multiple System Atrophy, a Case Trial
Objective: Iron removal seems to be a treatment approach in Multiple system atrophy (MSA) because pathological findings shows the accumulation of iron and α-synuclein protein…Prevalence of autonomic symptoms in Multiple System Atrophy on the background of probable RBD
Objective: To discover whether having probable rapid eye movement sleep behavior disorder (RBD) affects prevalence of particular autonomic symptoms, namely falls, constipation and urinary incontinence…Minimally Clinical Important Differences of Hemifacial Spasm Score-30 (HFS-30) and Hemifacial Spasm Score-7 (HFS-7) for Patients with Hemifacial spasm
Objective: We aimed to estimate the MCIDs of HFS-30 and HFS-7, and factors associated with the MCID along with baseline and change score of HFS-30…Dopamine transporter imaging to predict the risk of aspiration in patients with Parkinson’s disease
Objective: To assess the predictive performance of clinical measures, including dopamine transporter (DaT) imaging, for identifying aspiration risk in patients with Parkinson’s disease (PD). Background:…The Contribution of APOE4 Genotype on Structural MRI in Parkinson’s Disease: A Study from the PPMI Cohort
Objective: To assess the contribution of Apolipoprotein E4 (APOE4) in Parkinson’s Disease (PD)-related cognitive impairment by analyzing its impact on Gray Matter Volume (GMV). Background:…First in vivo evidence of the role of the noradrenergic system in olfactory dysfunction in Parkinson’s disease
Objective: To investigate the relationship between in vivo noradrenergic markers and olfactory impairment in patients with Parkinson’s disease (PD). Background: Degeneration of the noradrenergic (NA)…Serotonin Transporter Dynamics in Multiple System Atrophy: Insights from 123I-FP-CIT SPECT Imaging
Objective: We aimed to visualize a serotonin transporter (SERT) based on 123I-FP-CIT SPECT, and assessing the binding distribution characteristics of the brainstems between patients with…Comparative analysis of opicapone and entacapone in the management of motor fluctuations in patients with Parkinson’s disease, from clinical trials to healthcare resource usage
Objective: To assess the differences between two catechol-O-methyltransferase (COMT) inhibitors, opicapone (OPC) and entacapone (ENT). Background: Opicapone and ENT are COMT inhibitors developed as adjunct…From Images to Insights: Subtyping Parkinson’s Disease Using Unsupervised Learning on MRI Data
Objective: To explore the heterogeneity of Parkinson's disease (PD) using unsupervised clustering of neuroimaging data, aiming to identify distinct subtypes based on volumetric features. Background:…Association between statin use and mortality in Parkinson’s disease
Objective: To investigate whether usage of statin is associated with decreased mortality in Parkinson’s disease (PD). Background: Large-scale genome sequencing studies of PD have identified…
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