MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Stabilometry characteristics as objective Parkinson’s disease progression biomarkers

    I.V. Miliukhina, T.V. Sergeev, E.V. Gracheva, A.V. Kudrevatykh, M.D. Didur (Saint-Petersburg, Russia)

    Objective: We aimed to find stabilometry characteristics, which may be used as disease progression and postural instability early development markers. Background: Balance and gait disorders…
  • 2016 International Congress

    Generation and characterization of midbrain organoids from iPSCs of familial Parkinson’s disease

    E. Frattini, G. Monzio Compagnoni, S. Salani, P. Rinchetti, M. Nizzardo, M. Baccarin, N. Bresolin, G.P. Comi, S.P. Corti, A. Di Fonzo (Milan, Italy)

    Objective: To generate and characterize human pluripotent stem cell (iPSCs) - derived midbrain cerebral organoids of patients with Parkinson's disease. Background: Parkinson's disease is a…
  • 2016 International Congress

    Cyclic glycine-proline increased in the cerebrospinal fluid of Parkinson’s patients after supplementation of blackcurrant anthocyanins: Potential biomarker for treatment

    J. Guan, Y. Alamri, D. Fan, M. MacAskill, T. Anderson (Auckland, New Zealand)

    Objective: We evaluated the changes of insulin-like growth factor-1 bioavailability in the Parkinson's disease patients after 28 day supplementation of blackcurrant anthocyanin. Background: Elevated insulin-like…
  • 2016 International Congress

    In idiopathic Parkinson’s disease: The effect of using L-dopa on peripheral nerves

    M.E. Temir, F. Genç, Y. Biçer Gömceli, A. Yaman, A. Aybar, E. Karaçay (Antalya, Turkey)

    Objective: Idiopathic Parkinson's disease (IPD) is a chronic neurodegenerative disorder. Most of the clinicians believe that it is limited with motor and cognitive disorders. However,…
  • 2016 International Congress

    Cortical role in the freezing of gait in Parkinson’s disease

    M. Mihara, H. Otomune, H. Fujimoto, K. Konaka, Y. Watanabe, H. Mochizuki (Suita, Japan)

    Objective: In this study, we aimed to investigate the neural underpinning of freezing of gait (FOG) in Parkinson's disease (PD), especially the role of the…
  • 2016 International Congress

    Association of Parkinson’s disease severity and cortical and subcortical cognitive markers

    H. Duran-Meza, A.D. Santana-Vargas, J.D. Ramirez-Diossa, G.H. Terrazas Gonzalez, G. Millan-Rosas, U. Jimenez-Correa, M. Lopez-Ruiz (Mexico City, Mexico)

    Objective: To assess cortical and subcortical dysfunction in several stages of Parkinson's disease (PD) using the Parkinson's disease-cognitive rating scale (PD-CRS). Background: Cognitive impairment in…
  • 2016 International Congress

    Pathophysiological mechanisms of bone mass loss for osteoporosis prevalence in Parkinson’s disease

    L.A. Leandro, H.A.G. Teive (Curitiba, Brazil)

    Objective: Quantify the impact of osteoporosis in Parkinson's disease to know factors that caused bone loss. Background: Parkinson´s disease (PD) and osteoporosis are two conditions…
  • 2016 International Congress

    Glutathione status in Parkinson’s disease

    L.K. Mischley (Kenmore, WA, USA)

    Objective: Describe measures of glutathione (GSH) status in a cohort of individuals with Parkinson's disease (PD). Background: It is well established that redox stress contributes…
  • 2016 International Congress

    Intrastriatal injection of ionomycin profoundly changes motor response to L-DOPA and its underlying molecular mechanisms

    C. Han, S. Nie, G. Chen, K. Ma, N. Xiong, Z. Zhang, Y. Xu, T. Wang, S.M. Papa, X. Cao (Wuhan, People's Republic of China)

    Objective: We investigated whether intrastriatal injection of ionomycin to hemiParkinsonian rats produced changes in L-DOPA responses including LID and analyzed the effects of ionomycin on…
  • 2016 International Congress

    Lrrk2 alleles modify host response to microbial infections

    B. Shutinoski, I. Harmsen, M. Hakimi, Y.Y. Zhou, S. Sad, J.J. Tomlinson, E.G. Brown, M.G. Schlossmacher, CLINT Investigators (Ottawa, ON, Canada)

    Objective: The mechanisms by which allelic changes in LRRK2 modulate the susceptibility to Parkinson's disease, Crohn's disease and leprosy remain unknown. We hypothesized that leucine-rich…
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