1H-NMR and UPLC/MS Metabolomics Identify Disrupted Homeostasis of Energy, Amino Acids, and Glutathione Metabolism as Serum Signatures in Parkinson’s Disease Patients
Objective: We sought to identify a signature distinctive of Parkinson’s disease (PD) through two independent metabolomics approaches. Background: A recent meta-analysis showed a considerable inconsistency…Dried Plasma Spot Cards for Measurement of Neurofilament Light Chain
Objective: Evaluate measurement of neurofilament light chain (NfL) in dried plasma spot cards, and to compare these to measurements using more invasive and in person…Prevalence and Management of Depression Among Parkinson’s Patient’s in an Outpatient Clinic Setting
Objective: To evaluate the prevalence of depression among Parkinson’s Disease (PD) patients attending an outpatient clinic and review current management to improve diagnosis and treatment…Validation of CSF Alpha-synuclein SAA in an Autopsy Cohort with Systemic Assessment of Lewy Pathology Including the Body
Objective: Based on the recent recommendations by international neuropathologists [1], we attempted to evaluate the diagnostic accuracy of cerebrospinal fluid (CSF) alpha-synuclein (α-syn) seeding amplification…Alpha-Synuclein Preformed Fibrils Increase the Frequency of CXCR3+ B-cells in Early-stage Parkinson’s Disease Patients
Objective: To investigate the effect of a-Syn Preformed Fibrils (PFF) on CXCR3 expression on B-cells in Parkinson’s Disease (PD) patients at early (E-PD, diagnosed less…Medication therapy in Parkinson’s disease patients: a cross-sectional study at the University Medical Center at Ho Chi Minh City, Vietnam
Objective: To determine the rate of drugs prescribed to treat Parkinson's disease motor symptoms, the rate of the types of drug combinations, and the frequency…Quantitative Digitography and Home Diaries for PD Motor State Evaluation
Objective: Assess the feasibility of people with Parkinson’s (PwP) performing 30 seconds of repetitive alternating finger presses using Quantitative Digitography (QDG) technology every 30 minutes…Identification of Rigidity in Parkinson’s Disease Using Wearable Technology
Objective: To evaluate the capacity of upper limb kinematic measures, collected using wearable technology, in (a) capturing clinical rigidity in Parkinson’s disease (PD) and (b)…The role of interoception in motor imagery in Parkinson’s disease
Objective: The present study explored the relationship between interoceptive awareness and motor imagery in individuals with PD. Background: Motor imagery is the imagination of movement,…Tracking Cognitive Decline and Understanding Study Dropout in PD-GBA
Objective: Analyze which cognitive functions are affected in PD_GBA+, and which factors are linked to dropout risk. Background: People with Parkinson's disease (PD) who carry…
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