A multiple-dose thorough QT study to evaluate the effect of ampreloxetine on cardiac repolarization in healthy subjects
Objective: To characterize the effect of therapeutic and supratherapeutic doses of ampreloxetine on cardiac repolarization in healthy subjects. Background: Ampreloxetine is a potent NE reuptake…Late Onset Cerebellar Ataxia in a Patient with a Heterozygous Pathogenic KIF1A Mutation: A Case Report
Objective: Expand upon the current phenotypic understanding of those with KIF1A-associated neurological disorder (KAND), including late onset progressive cerebellar ataxia (CA). Background: KAND encompasses a group…Correlation between Striatal degeneration and Cerebellar fiber alterations of Parkinson’s disease
Objective: We tried to show divisional evaluation of caudate and putamen in [123I] FP-CIT(DAT) -SPECT has use for assessment of PD symptoms and capture the…Longitudinal changes in brain networks associated with clinical symptoms in idiopathic rapid eye movement sleep behavior disorder
Objective: We aimed to assess changes in brain functional networks and accompanying symptoms over years in patients with idiopathic rapid eye movement sleep behavior disorder…Reconstruction of the dentato-rubro-thalamic tract based on the anatomy of the rubral wing
Objective: We investigated reconstructing the entire dentato-rubro-thalamic tract (DRT) by an anatomical “rubral wing”-based tractography and compare its correlation with clinical outcomes to those of…A retrospective comparison of functional and quality of life outcomes in DBS patients implanted via awake or asleep surgery: the Rush University Medical Center experience
Objective: We retrospectively compared quality of life and functional status metrics to assess differences among patients who underwent implantation of Deep Brain Stimulation (DBS) for…Nucleus basalis of Meynert and total gray matter atrophy are related to cognitive and gait decline in Parkinson’s disease
Objective: To assess the associations between the nucleus basalis of Meynert (NBM) and total grey matter atrophy with cognitive phenotype and gait measures in a…Exploring the Effects of Spinal Cord Stimulation for Gait Disturbances in Parkinson’s Disease
Objective: We sought to investigate the effects of SCS in PD, using placebo stimulation, compared to either tonic or burst stimulation paradigms. Background: Gait disturbances…Sleep hygiene practice in patients with Parkinson’s disease
Objective: We examined the prevalence of diverse sleep hygiene behavior and their associations with insomnia severity in PD patients.We examined the prevalence of diverse sleep…Feasibility and acceptability of implementing dignity therapy as a supportive intervention for people with movement disorders.
Objective: To determine the feasibility and acceptability of implementing Dignity Therapy (DT) in a neuropalliative clinic, and to determine preliminary efficacy. Background: Awareness of the…
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