Mechanical and thermal thresholds in the MPTP macaque model of Parkinson’s disease
Objective: To characterise the mechanical and thermal thresholds in the MPTP macaque model of Parkinson’s disease (PD). Background: Many PD patients suffer from some form…Perspective of people living with early Parkinson’s Disease: most common, burdensome, and worrisome symptoms
Objective: To assess the most common, burdensome and worrisome symptoms experienced by people living with early Parkinson’s Disease (ePD). Background: Research on symptom frequency and…Autonomic Dysfunction in Parkinson’s Disease Link with disease severity and other non-motor signs
Objective: Clarify the relationship between autonomic dysfunction, disease severity and NMS in PD patients. Background: Parkinson’s disease (PD) is characterized by a combination of motor…Comparative Effectiveness of Behavioral or Drug Therapy for Overactive Bladder Symptoms in Parkinson Disease
Objective: Assess the comparative effectiveness of behavioral or solifenacin drug therapy over 12 weeks for overactive bladder (OAB) symptoms according to the International Consultation on…Abnormal Top-down Perceptual Modulation Drives Visual Hallucinations in Parkinson’s Disease
Objective: Assess performance on computerized illusions across PD patients with (PD_Hal) and without (PD_NonHal) history of visual hallucinations and explore underlying cortical substrates. Background: In…Clinical and Neuroimaging Biomarker Predictors of Cognitive Dysfunction In Parkinson’s Disease: A Study Using PPMI Data
Objective: This study evaluates whether clinical, biological, and neuroimaging baseline markers can predict the onset of significant cognitive-based milestones developed in these cohorts over a…How Does Mild Cognitive Impairment in Parkinson’s Disease Affect Communication Abilities?
Objective: We explored differences in communication abilities in people with Parkinson’s disease (PwP) with mild cognitive impairment (MCI) (PwP-MCI) and those with normal cognition (PwP-CN).…Episodes of Hypoglycemia in Patients with Parkinson’s Disease – Results of Two-Week Continuous Glucose Monitoring
Objective: The study aimed to determine the incidence of hypoglycemic episodes in patients with Parkinson's disease (PD) and assess risk factors for these episodes. Background:…Brainstem Monoaminergic Degeneration, Cognition, and Autonomic Symptom Progression in Early Parkinson’s Disease
Objective: In this study, we aimed to investigate the association between brainstem monoaminergic nuclear degeneration, particularly the serotonergic raphe and noradrenergic locus coeruleus, and cognitive…Subtyping Parkinson’s Disease Mild Cognitive Impairment (PD-MCI) by Cholinergic Degeneration
Objective: This study aims to investigate whether PD-MCI patients exhibiting cholinergic degeneration, evidenced by reduced Ch4 grey matter density (GMD) on brain MRIs, constitute a…
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