Study protocol for the iMarkHD study in individuals with Huntington’s disease
Objective: To describe the study protocol for the iMarkHD study. Background: Huntington’s disease (HD) is still often defined by the onset of motor symptoms, inversely…Neurite Orientation Dispersion and Density Imaging and Diffusion Kurtosis Imaging in Brainstem Nuclei for Subtypes of Parkinson’s Disease
Objective: We utilized neurite orientation dispersion and density imaging (NODDI) along with diffusion tensor and kurtosis imaging (DTI/DKI) to assess brainstem nuclei in Parkinson’s disease…Automated parcellation of the cerebellum in patients with newly diagnosed Parkinson’s disease
Objective: Quantitatively evaluate the gross morphology of individual cerebellar lobules, determine whether cerebellar anatomical changes occur early in the disease and whether changes were related…Basal ganglia shape in de novo Parkinson’s disease patients can predict the onset of Levodopa Induced Dyskinesias
Objective: In the current study, we aimed to examine structural MRI data from a large sample of de novo PD patients and to identify potential…White matter lesion burden is associated with poorer clinical and driving outcomes in mild Parkinson’s disease
Objective: To determine association of brain white matter microvascular lesion burden with cognition, motor function, and driving in mild Parkinson’s disease (PD). Background: Brain white…White matter lesions and motor symptoms in Parkinson’s disease
Objective: Objective: To investigate the association between cerebral white matter lesions (WML) and motor symptoms in Parkinson’s disease (PD). Background: Background: Previous studies have shown…Pallidal or subthalamic DBS for advanced Parkinson’s disease in the era of high-resolution MRI
Objective: We aimed to assess outcome of GPi-DBS and STN-DBS implanted based on high-resolution MRI. Background: Both GPi-DBS and STN-DBS are effective for treatment of…Regional Atrophy and Motor Speech in PSP
Objective: This study examined the association of regional atrophy on MRI and motor speech in PSP. Background: Motor speech impairment is common in PSP[1]. Although…Cortical mean diffusivity changes in Parkinson’s disease with probable RBD
Objective: To investigate cortical mean diffusivity (cMD) as a sensitive measure to identify subtle microstructural cortical changes in Parkinson’s disease (PD) patients with probable REM…Multimodal neuroimaging to probe brain networks in Cervical Dystonia.
Objective: We employed a multimodal approach to gain a comprehensive understanding of the pathophysiology of cervical dystonia. The aim was to assess behavioural, microstructural, and…
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