Structural magnetic resonance imaging patterns reflect α-synuclein propagation in a model of Parkinson’s Disease
Objective: To evaluate structural magnetic resonance imaging (MRI) pattern modifications in an α-synuclein model of Parkinson’s disease (PD). Background: As an early driver of α-synucleinopathies’…The Contribution of APOE4 Genotype on Structural MRI in Parkinson’s Disease: A Study from the PPMI Cohort
Objective: To assess the contribution of Apolipoprotein E4 (APOE4) in Parkinson’s Disease (PD)-related cognitive impairment by analyzing its impact on Gray Matter Volume (GMV). Background:…Evaluation of Glymphatic System Function in Parkinson’s disease patients using Diffusion MRI
Objective: To investigate the activity and clinical significance of glymphatic system in Parkinson's disease (PD) patients using diffusion MRI. Background: Although much research on proteinopathies…Transition from Zinc Salts to Trientine Tetrahydrochloride in Wilson Disease: Clinical and Biochemical Effects over Two Years – the ZICUP study
Objective: To assess the clinical and biochemical effects of transitioning from zinc salts (ZS) to trientine tetrahydrochloride (TETA4HCL) in Wilson disease (WD) patients over a…Reduced Thalamic Nuclei Volume May Contribute to Anxiety in Parkinson’s Disease: a 7-Tesla MRI Study
Objective: To identify changes in volume of the thalamus and its subnuclei in patients with Parkinson's disease (PD) related anxiety. Background: PD-related anxiety occurs frequently…Hippocampal volume in Parkinson’s Disease in south India
Objective: To analyse hippocampal volume differences among the patients with Parkinson’s disease and healthy individuals. Background: In humans, hippocampus is involved in regulation of emotions,…Severity of Motor Symptoms Correlates with Asymmetric Changes in Globus Pallidus Internus and Caudate Nuclei in Parkinson’s Disease
Objective: Explore the relationship between MDS-UPDRS motor sub-scores (MDS-UPDRS-III) and cerebral perfusion in different Regions of Interest (ROI) in patients with Parkinson’s disease (PwP). Background:…Predictive Value of Brain Structural Changes on Motor Outcomes Following VIM Thalamotomy in Essential Tremor: Preliminary Results
Objective: To identify structural MRI factors that correlate with variations in motor outcomes for essential tremor (ET) patients after Gamma Knife thalamotomy (GKT). Background: Stereotactic…Clinical spectrum of repetitive behaviours and neuroimaging findings in adult patients with neurological Disorders: a cross-sectional Observational study
Objective: This study aimed to report the detailed clinical profile of repetitive behaviours in adult patients with neurological disorders. Background: Repetitive behaviours are observed in…Selecting an Imaging Biomarker for a Multi-Arm Multi-Stage Trial of Disease-Modifying Treatments for Parkinson’s: The EJS ACT-PD Experience
Objective: To report on the selection of an imaging biomarker for a sub-study in a multi-arm, multi-stage (MAMS) platform trial for disease-modifying therapies (DMTs) in…
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