Describing the syndrome: a comprehensive analysis of a large cohort of corticobasal syndrome with pathological correlation
Objective: To describe the clinical, biomarker, genetic and pathological features of a cohort of patients with corticobasal syndrome (CBS). Background: Corticobasal degeneration (CBD) was first…6-[18F]fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET striatal binding patterns in patients with Parkinson’s Disease and Parkinson Plus Syndromes.
Objective: In this study we investigate striatal binding patterns in patients with Idiopathic Parkinson’s disease (IPD), compared to those with Parkinson Plus syndromes (PPS) versus…Case report- Cavernoma involving substantia nigra and nigrostriatal pathway as a rare cause of secondary parkinsonism with a 3 year follow up
Objective: To describe a case report of a rare cause of Parkinsonism Background: Vascular malformations such as cerebral cavernomas are known to predispose to haemorrhagic…Wilson disease: a single-center study from Tunisia
Objective: We aimed to describe different clinical and radiological presentations of WD and insist on the necessity of early diagnosis to ensure therapeutic efficiency. Background:…Data-driven Clustering of Neurodegenerative diseases based on EEG Spectrum power-law decay: the DaCNES Study.
Objective: To test accuracy of the power law exponent β applied to EEG in differentiating neurodegenerative diseases and to explore differences in neuronal connectivity among…Early-onset levodopa-responsive Parkinsonism associated with dysarthria, pyramidalism, and dystonia: a rare condition that can benefit from a combined treatment approach.
Objective: To describe a rare case of early-onset parkinsonism (EOP) successfully treated with a combined therapeutic approach. Background: EOP is a rare condition manifesting with…Idiopathic Intracranial Hypertension as the presenting symptom in Wilson’s Disease: how is it possible?
Objective: To report a patient with Wilson’s disease (WD) who became symptomatic shortly after presenting Idiopathic Intracranial Hypertension (HII). Background: WD’s pleomorphic clinical phenotype remains…Clinical, radiological and genetic spectrum of fifteen cases of PLA2G6-Associated Neurodegeneration – A Single Centre Cohort from India
Objective: To study the clinical, radiological and genetic profile of patients with genetically proven PLA2G6-Associated Neurodegeneration (PLAN). Background: PLAN is a clinically heterogenous genetic disorder…Correlation between Motor Sections of UMSARS and MDS-UPDRS
Objective: To determine the correlation between UMSARS II and MDS-UPDRS III. Background: Despite the availability of the Unified Multiple System Atrophy Rating Scale (UMSARS) [1]…Contribution of MRI and machine learning approaches to the diagnosis of patients with early-stage parkinsonism in a situation of clinical uncertainty
Objective: To determine whether MRI and machine learning approaches improve diagnostic accuracy in patients with early-stage parkinsonism compared to clinical criteria Background: Parkinson’s disease (PD)…
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