A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson’s Disease (PADOVA): Rationale, Design, and Baseline Data
Objective: The study will evaluate the efficacy and safety of prasinezumab in individuals with early-stage Parkinson's disease (PD) on stable symptomatic therapy. Background: Available treatments…Effect and Mechanism of Shaoyao Gancao Decoction(SGD) in Treatment of Pain in Parkinson’s Disease Based on Network Pharmacology and Molecular Docking
Objective: Based on the method of network pharmacology, this paper discusses the potential effects and mechanisms of SGD in the treatment of pain in PD. Background:…Clinical-based diagnosis and self-reported Parkinson’s disease in a population-based sample in southern Brazil
Objective: To report the frequency of self-reported PD and the diagnostic evaluation performed by clinical neurologists in a population-based cohort from south Brazil. Background: It…Transcranical Pulse Stimulation in Parkinson’s rest tremor: a pilot study.
Objective: The goal of this paper is to explore a possible effect of TPS on the PD rest tremor circuit, stimulating the motor cortex (M1)…Machine learning reveals candidate genes from Parkinson’s disease associated loci
Objective: To prioritize candidate genes from Parkinson's disease (PD) genome-wide association studies (GWAS) for future functional studies. According to PubMed, most of the field still…Cognitive assessment of Parkinson’s disease carriers of the novel p.A30G mutation in the SNCA gene
Objective: The aim of the present report was to evaluate the cognitive profile of symptomatic Parkinson’s disease (PD) patients in a p.A30G SNCA genetic cohort.…Comparing neuromelanin intensity estimation techniques for Parkinson’s disease image analysis
Objective: The objective of this study is to compare robust neuromelanin (NM) substantia nigra pars compacta (SN) and locus coeruleus (LC) quantification techniques captured in…Accelerated longitudinal brain atrophy in the ‘diffuse malignant’ Parkinson’s disease subtype
Objective: To investigate differential pattern of brain atrophy between Parkinson’s disease (PD) clinical subtypes using longitudinally acquired brain magnetic resonance imaging (MRIs). Background: Parkinson’s disease…Verbal Fluency Changes After Unilateral STN Deep Brain Stimulation in Parkinson’s Disease: A Connectomics-Based Approach
Objective: To investigate neural circuitry associated with verbal fluency changes after STN-DBS in Parkinson’s disease. Background: Despite its substantial motor benefits, subtle cognitive changes can…Adequate hydration with personalized diet improves bowel function and mobility for people with Parkinson’s (PwP’s) on levodopa/carbidopa intestinal gel (LCIG) infusion therapy
Objective: To investigate the effect of the adequate hydration with personalized diet on bowel function, motor function, and global function in PwP’s on LCIG. Background:…
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