Neurosonography of substantia nigra in patients with isolated essential tremor and in association with Parkinson’s disease of the family nature
Objective: To identify differential clinical and neurosonographic criteria for ET and PD in patients with familial ET. Background: ET and PD are common disorders, especially…Transcranial sonography in HIV infection: Does it reflect infectious and neurological symptoms?
Objective: To study whether transcranial sonography of brain parenchyma shows features with a potential association with clinical and neurological variables in human immunodeficiency virus (HIV)…Substantianigral involvement on Tc99mDaTSPECT-a novel and under recognised imaging finding in Parkinsonian Disorders
Objective: To assess feasibility of identifying SN involvement on DaTi, correlate with laterality of motor symptoms and compare with loss of nigrosome-1 hyperintensity on SWI . Background:…Targeted deep sequencing of brain DNA for detection of somatic point mutations in synucleinopathies
Objective: To detect relevant somatic "point mutations" (single nucleotide variants- SNVs) in brain-derived DNA in synucleinopathies. Background: There is increasing recognition that neurons may harbour…Sequencing of single human nigral dopaminergic neurons for somatic copy number variants
Objective: To detect somatic DNA copy number variants (CNVs) in dopaminergic neurons isolated from human substantia nigra, using shallow whole genome sequencing (WGS). Background: Somatic…The trace of substantia nigra hyperechogenicity: a clinical observation
Objective: To present an empirical observation regarding transcranial ultrasound in movement disorders and scalp sebum smear. Background: Transcranial ultrasound (TUS) detects substantia nigra hyperechogenicity (SN+) in…Transcranial ultrasound in atypical parkinsonism: how reliable is it in real clinical practice? A multi-centre comprehensive study
Objective: To assess real clinical practice usefulness of transcranial ultrasound in atypical parkinsonism differential diagnosis, and to perform a critical analysis of previous literature in…Substantia Nigra Hyperechogenicity in Parkinson’s Disease and Essential Tremor and its Association with Premotor Symptoms of Parkinson’s Disease
Objective: To compare the frequency of Substantia Nigra hyperechogenicity (SN+) in patients with essential tremor (ET) and Parkinson’s disease (PD), to determine the frequency of…Evaluation of nigral neuronal apoptosis during postnatal development and adulthood of mice strains with differential sensitivity to MPTP
Objective: Compare nigral neurons in C57BL/6J, CD-1 and their F1 crossbreds with respect to developmental apoptosis in the nigra during postnatal and to assess MPTP-induced…Caudal posterior substantia nigra iron increases longitudinally in Parkinson’s disease
Objective: To investigate spatial patterns and temporal evolution of substantia nigra (SN) iron accumulation in Parkinson’s disease (PD) using quantitative susceptibility mapping (QSM), an indirect…
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