Managing Cognitive Decline in Vascular Dementia with Associated Parkinsonism
Objective: The intersection of vascular dementia (VaD) and secondary parkinsonism presents a complex therapeutic conundrum, particularly in geriatric populations. This study aims to elucidate the…Cognitive Performance in Early Neuronal alpha-Synuclein Disease
Objective: To determine if cognitive deficits can be detected in early-stage Neuronal alpha-Synuclein Disease (NSD) compared with healthy controls. Background: Global cognitive deficits have been…Frontal dysfunction as a cognitive biomarker in prodromal Parkinson’s disease
Objective: To assess specific cognitive biomarkers to increase the sensibility for the diagnosis of Prodromal Parkinson’s disease (pPD) that could help to identify these patients.…Impact of Striatal Degeneration on Clinical Phenotype in Idiopathic Normal Pressure Hydrocephalus: A Comparative Analysis
Objective: To compare the clinical phenotype between patients with normal and abnormal dopamine transporter scan (DaTscan) in probable and definite idiopathic normal pressure hydrocephalus (iNPH).…A Phase 2 Study of ATH434 a Novel Inhibitor of α-Synuclein Aggregation for the Treatment of Multiple System Atrophy
Objective: Describe baseline fluid and neuroimaging biomarker data of an early MSA study population Background: MSA is a rapidly progressive neurodegenerative disorder characterized by aggregated…A 3D CNN Approach for the Classification of Multiple System Atrophy using Multimodal Multicentric MRI
Objective: To automatically distinguish between healthy controls (HC) and patients with multiple system atrophy (MSA) with a completely automatic approach using a 3D convolutional neural…Assessment of cognitive impairment in Parkinson’s disease in under-represented ethnic groups-The London-Dhaka Parkinson’s Cognitive Study
Objective: The aim of this study is to evaluate the prevalence of CI in a diverse group of PwP from East London, UK and Dhaka,…Periodic and Aperiodic EEG Correlates of Cognition in Parkinson’s Disease
Objective: To examine periodic and aperiodic EEG correlates of cognition in Parkinson’s disease (PD). Background: Quantitative EEG metrics are increasingly used to describe variations in…Cleaved plasma kininogen is associated with unfavorable cognitive outcome in Parkinson’s disease
Objective: The aim of this study was to examine the association between kininogen cleavage in plasma and cognitive outcome in Parkinson’s disease (PD). Background: No…Optical Coherence Tomography Findings in Multiple System Atrophy: Insights into Disease Subtypes, Clinical Correlations, and Dopaminergic Degeneration
Objective: This study aimed to evaluate optical coherence tomography (OCT) findings in multiple system atrophy (MSA) patients, with a focus on disease subtypes, clinical correlations,…
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