MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2024 International Congress

    Expanding the phenotypic spectrum of movement disorders in 22q11.2 deletion syndrome

    N. Reyes, T. Cortez-Grippe, M. Callister, T. Heung, A. Bassett, A. Lang (Toronto, Canada)

    Objective: To formally characterize the evolving spectrum of movement disorders associated with chromosome 22q11.2 deletion syndrome Background: Emerging evidence suggests that a wide range of…
  • 2024 International Congress

    Moderate-to-severe upper limb spasticity patterns in the elderly are improved following treatment with incobotulinumtoxinA: a pooled analysis

    M. Munin, A. Camões-Barbosa, C. Cordero-García, M. Althaus, G. Comes, M. Vacchelli, C. Walter, J. Wissel (Pittsburgh, USA)

    Objective: To compare upper limb spasticity (ULS) severity changes from baseline in different spastic patterns at 4 weeks and 12 weeks post-injection of incobotulinumtoxinA (incoA)…
  • 2024 International Congress

    The Intention Component of Postural Tremor in Essential Tremor

    K. Valestrino, P. Kassavetis (Salt Lake City, USA)

    Objective: This study seeks to better characterize postural tremor in ET and to investigate the effect of intention and visual input on the amplitude and…
  • 2024 International Congress

    A Homozygous Variant in NAA60 is Associated with Primary Familial Brain Calcification

    X. Chen, Y. Shi, F. Fu, L. Wang, D. Yang, X. Wang, C. Ying, H. Wang, Z. Lin, H. Wang, F. Zhang, X. Zheng, Y. Guo, Y. Wang, Y. Zeng, M. Zhao, Y. Chen, J. Li, H. Xia, J. Chen, B. Wang, S. Wu, F. Xie, J. Feng, Z. Cen, W. Luo (Hangzhou, China)

    Objective: To identify novel genes in autosomal recessive Primary Familial Brain Calcifications (PFBC).To identify novel genes in autosomal recessive Primary Familial Brain Calcifications (PFBC). Background:…
  • 2024 International Congress

    MRgFUS thalamotomy for essential tremor: Lesion location and clinical outcomes

    M. Rodriguez-Oroz, AA. Arcadi, LGQ. Gonzalez Quarante, IA. Aviles-Olmos, AMB. Bastidas, AJH. Jimenez Huete, AG. Gorospe, JG. Guridi (Pamplona, Spain)

    Objective: To examine the clinical outcomes and their relationship with patients’ baseline demographic and clinical features and lesion characteristics at 6-month follow-up in ET patients.…
  • 2024 International Congress

    New Pathological Findings in an International Cohort of Hereditary Spastic Paraplegia 4 Patients

    A. Orlacchio, A. Meyyazhagan, P. Eusebi, P. Basavaraju, H. Kuchi Bhotla, M. Stasi, G. Ribas, I. Faber, R. Miyamoto, M. Miele, R. Massa, P. Patti, M. França Jr, J. Pedroso, O. Barsottini, H. Teive, T. Kawarai, E. Panza (Perugia, Italy)

    Objective: To determine the clinical and genetic differences in hereditary spastic paraplegia SPG4 patients across various countries. Background: SPG4/SPAST gene account for approximately 40% of…
  • 2024 International Congress

    Suvecaltamide Metabolites Are CaV3 Modulators and Contribute to Pharmacological Effect

    E. Brigham, W. Zeng, N. Shanks, M. Lee (Palo Alto, USA)

    Objective: To determine the potency-concentration relationships and combined pharmacological effects for suvecaltamide and its 2 active metabolites (JZZ05000034=M01, JZZ05000035=M02; total active moiety [TAM]). Background: T-type…
  • 2024 International Congress

    A prospective study on post-stroke Holmes tremor with analysis of semiology, lesion topography and treatment outcomes

    A. Datta, A. Mukherjee, A. Biswas (Kolkata, India)

    Objective: We aimed to (1) estimate incidence of HT following stroke at a tertiary care centre, (2) study and identify patterns of stroke lesions which…
  • 2024 International Congress

    Safety of staged bilateral MR-guided focused ultrasound thalamotomy for essential tremor

    M. Kaplitt, H. Sarva, V. Krishna, HM. Eisenberg, WJ. Elias, P. Ghanouni, GH. Baltuch, A. Rezai, C. Halpern, B. Dalm, P. Fishman, V. Buch, S. Moosa, AM. Murray (New York, USA)

    Objective: To evaluate the efficacy and safety of staged bilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy in patients with medication-refractory bilateral essential tremor (ET). Herein,…
  • 2024 International Congress

    A Phase IIb Double-Blind Placebo-Controlled Randomized Cross-Over Clinical Trial of Sodium Oxybate in Isolated Focal Laryngeal Dystonia

    L. O'Flynn, A. Hamzehei Sichani, S. Frucht, A. Rumbach, N. Sharma, P. Song, A. Worthley, K. Simonyan (Boston, USA)

    Objective: A phase IIb double-blind, placebo-controlled, cross-over, randomized clinical trial of a single dose of sodium oxybate investigated the efficacy and safety of the drug…
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