Ataxia, deafness, aphonia associated with ANNA-1/ /”anti-Hu” and LUZP4 antibodies
Objective: To describe the first case of primary mediastinal seminoma resulting in paraneoplastic syndrome (rhombencephalitis) secondary to two antibodies ANNA-1 and LZUP4. Background: Paraneoplastic neurological…Validation of the Patient Reported Outcomes in Parkinson’s Disease scale in outpatients
Objective: To validate PRO-PD in a random sample of outpatients with PD. Background: Successful treatment of Parkinson's disease (PD) requires symptom monitoring. Patient-Reported Outcomes in…Integrated safety analysis of BIA-28-6156 phase 1 clinical trials (a novel allosteric activator of beta-glucocerebrosidase)
Objective: To describe the safety profile and tolerability of BIA-28-6156 observed during phase 1 clinical trials. Background: BIA-28-6156 is a novel allosteric activator of beta-glucocerebrosidase…Advanced programming strategies in subthalamic DBS: Just a gimmick or well-established in clinical routine?
Objective: To evaluate the application of commonly available advanced programming strategies in deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson’s…Learnings from inaugural year of foundation sponsored genetic counseling and testing program for Spinocerebellar Ataxia (SCA) types 1, 2, and 3
Objective: To describe volume, genetic results, and participant perceptions of foundation sponsored genetic counseling and testing program for SCA 1, 2, and 3. Background: Molecular…Impulse Control Disorder and medication management in Patients with Early-Onset Parkinson’s Disease
Objective: To assess the usage frequency of dopamine agonists (DA), the prevalence of impulse control disorder (ICD) in patients with Early-onset Parkinson’s Disease (EOPD), and…Case report on the use of a High Frequency Vibrotactile Stimulation and Cueing Device over 4 months in a patient with Parkinson’s Disease and refractory symptoms
Objective: To document motor symptoms of a patient with PD whilst using a Focussed Vibrotactile Stimulation and Cueing Device (FVCD). Background: A 77-year-old patient with…Functional connectivity fingerprints in Parkinson’s disease patients with hallucinations
Objective: Investigate functional connectivity (FC) fingerprints of Minor Hallucinations (MH) in Parkinson’s Disease (PD). Background: MHs occur at the early stages of Parkinson’s disease in…Analysis of the network of genes related to Parkinson’s and identification of key proteins
Objective: Parkinson's disease (PD) is one of the increasing age-related diseases with no definite treatment. PD is considered as a disorder with genetic and non-genetic…Effort-based decision-making and neuropsychiatric symptoms before and after subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: Parkinson’s disease patients with apathy and patients in the medication OFF state show reduced reward sensitivity in effort-based decision-making tasks. The effect of subthalamic…
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