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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2022 International Congress » Parkinson's Disease: Neuroimaging

Meeting: 2022 International Congress

A brainstem-oriented PET/NMR method in Parkinson’s disease

Q. Demonceau, G. Demonceau, V. Lebon (Orsay, France)

Aberrant Volume-wise and Voxel-wise Concordance among Dynamic Intrinsic Brain Activity Indices in Parkinson’s Disease

T. Yuan, L. Kai, S. Wen (Beijing, China)

Activity and sleep associated with changes in glymphatic imaging-markers in Parkinson Disease patients enrolled in 3-month exercise program

J. Elenberger, J. Eisma, K. Hett, A. Song, C. Mcknight, Y. Yan, H. Kang, M. Donahue, D. Claassen, C. Considine (Nashville, USA)

Altered visual network dynamics associated with freezing of gait in Parkinson’s disease

D. Su, L. Ji, Y. Cui, J. Zhou, T. Wu, J. Stoessl, Y. Liu, T. Feng (Beijing, China)

Amygdala-hippocampus damage critically contributes to visual dysfunction in Parkinson disease

P. Reyero, A. Erramuzpe, A. Murueta-Goyena, A. Jimenez-Marin, M. Acera, S. Teijeira-Portas, B. Tijero, R. Del Pino, T. Fernández-Valle, O. Lucas-Jiménez, N. Ibarretxe-Bilbao, U. Ayala, M. Barrenechea, A. Cabrera-Zubizarreta, J. Cortes, J. Gomez-Esteban, I. Gabilondo (Barakaldo, Spain)

An automated data cleaning approach to remove preparation artefacts from brain histology slide images

V. Giunchiglia, S. Gentleman, R. Nicholas (London, United Kingdom)

Artificial Intelligence based detection of Parkinson’s disease in Magnetic Resonance Imaging brain scans

M. Courtman, M. Thurston, L. Mcgavin, C. Carroll, L. Sun, E. Ifeachor, S. Mullin (Plymouth, United Kingdom)

Assessment of microstructural changes associated with levodopa-induced dyskinesia in hemiparkinsonian rodents

M. Bergamino, A. Fuentes, D. Marmion, I. Sandoval, C. Bishop, F. Manfredsson, A. Stokes (Phoenix, USA)

Assessment of novel diffusion MRI metrics of cortical microstructure in the genetic continuum of Parkinson’s disease

M. Torso, D. Tzaferou, M. Valotti, J. Hardwidge, I. Hardingham, Q. Guo, R. Comley, S. Chance, G. Ridgway (Oxford, United Kingdom)

Association between longitudinal degeneration of the cholinergic basal forebrain and cognition-relevant cortical areas in early-stage PD

M. Labrador-Espinosa, J. Silva-Rodríguez, P. Mir, M. Grothe (Sevilla, Spain)

Basal forebrain contribution to cognitive deficits during medication “off” state in Parkinson’s disease

D. Lench, T. Turner, E. Woolbright, F. Rodriguez-Porcel, G. Revuelta (Charleston, USA)

Beyond the subthalamic nucleus: tractography patterns of Magnetic Resonance-guided Focused Ultrasound subthalamotomy

R. Rodriguez-Rojas, JU. Mañez-Miro, JA. Pineda-Pardo, R. Martinez-Fernandez, M. Del Alamo, JA. Obeso (Madrid, Spain)

Brain effects of high-intensity exercise on the dopamine system in individuals with Parkinson’s disease

S. Tinaz, B. de Laat, G. Stanley, J. Hoye, J. Key, M. Hespeler, J. Ligi, Y. Huang, N. Nabulsi, E. Morris (New Haven, USA)

BRAIN REGIONAL HYPOMETABOLISM PROGRESSION IN iRBD: THE COGNITIVE ROLE OF OCCIPITAL HYPOMETABOLISM

G. Carli, S. Meles, A. Janzen, D. Perani, W. Oertel, K. Leenders (Groningen, Netherlands)

Cerebro-cerebellar motor networks in clinical subtypes of Parkinson’s disease

F. Agosta, S. Basaia, A. Francia, C. Cividini, R. Balestrino, T. Stojkovic, I. Stankovic, V. Markovic, E. Sarasso, A. Gardoni, R. de Micco, L. Albano, E. Stefanova, VS. Kostic, M. Filippi (Milan, Italy)

Characterization of neuromelanin MRI as a potential Parkinson’s Disease biomarker in a multi-site longitudinal study

M. Ingalhalikar, H. Pham, L. Bracoud, RM. Hutchison, K. Evans, T. Dam, M. Sampat, J. Schaerer, C. Conklin, J. Suhy, D. Scott (San Mateo, USA)

Cholinergic Nucleus 4 Degeneration and Cognitive Impairment in REM Sleep Behavior Disorder

C. Tan, H. Nawaz, S. Lageman, B. Berman, N. Mukhopadhyay, M. Barrett (Richmond, USA)

Clinical Characteristics of patients with Parkinson’s disease showing normal values on SBR in the DAT SPECT

M. Nomoto, C. Ochi, R. Ando, Y. Murakami (Imabari, Ehime, Japan)

CLINICAL CORRELATION OF VISUAL LEUKOARAIOSIS SCALES AND VOLUMETRIC ANALYSIS IN PATIENTS WITH ISCHEMIC CEREBRAL VASCULAR EVENT AND PARKINSON’S DISEASE.

C. Cerda-Contreras (Monterrey, N.L., Mexico)

Cortical beta activity in doorway-provoked motor blocks in Parkinson’s disease

S. Tran, J. Baarbe, R. Chen (Toronto, Canada)

DaTscan striatal binding ratio dynamics in mutations carriers at risk for Parkinson’s disease: A 2-year prospective study

A. Droby, D. Atias, H. Lerman, RM. Hutchison, L. Yahimovich, J. Cedarbaum, E. Even Sapir, N. Giladi, A. Mirelman, A. Thaler (Tel Aviv, Israel)

Decrease of striatal activity during the execution of a everyday-life motor habits in early Parkinson’s disease.

P. Guida, M. Michiels, M. H Monje, J. Obeso, I. Obeso (Móstoles, Spain)

Deep learning applied to retinal OCT images to differentiate Parkinson’s disease patients from healthy controls

M. Barrenechea, D. Romero-Bascones, A. Murueta-Goyena, JC. Gomez-Esteban, A. Alberdi, A. Erramuzpe, U. Ayala, I. Gabilondo (Mondragon, Spain)

Diagnostic accuracy of dopamine SPECT in degenerative parkinsonism compared to neuropathological diagnosis.

A. Hastings, H. Morris, Z. Jaunmuktane, T. Warner, E. de Pablo-Fernandez (London, United Kingdom)

Diagnostic Utility of I123-FP-CIT Single Photon Emission Computed Tomography for Patients with Clinically Uncertain Parkinsonian Syndrome

R. Falconer, T. Hunter, E. Szabo, C. Brand (Alexandria, USA)

Diagnostic value of striatal [18F]-FP-DTBZ PET in Parkinson’s disease

X. Liu, S. Liu, O. Barret, G. Tamagnan, H. Qiao, T. Song, C. Piu, J. Lu (Beijing, China)

Different longitudinal manifestations in dopaminergic dysfunction in REM sleep behavior disorder

P. Wu, H. Yu (Shanghai, China)

Diffusion-weighted imaging based free-water investigation in Parkinsonian disorders

AKS. Shah, JS. Saini, MI. Ingalhalikar, SP. Prasad, PKP. Pal (Pune, India)

Distinct Patterns of Tremor Network Microstructure for Essential Tremor and Parkinson’s Disease

T. Welton, A. Ong, S. Hartono, Y-C. Shih, A. Lee, E-K. Tan, L-L. Chan (Singapore, Singapore)

Diverse alteration of brain networking in PD with ICD-RBs

YJ. Guo, CM. Chen, JR. Duann, MK. Lu, MH. Chang (Taichung, Taiwan)

Does autosomal recessive Parkinson’s Disease behave as “Brain-first” subtype?

B. Soydas-Turan, G. Yalcin-Cakmakli, B. Volkan-Salanci, E. Lay-Ergun, B. Elibol (Ankara, Turkey)

Dopaminergic Denervation as Predictors of Axial Dysfunction in Parkinson’s Disease

J. Li, N. Phielipp (Irvine, USA)

Dopaminergic Denervation as Predictors of Falls in PD Patients

J. Li, N. Phielipp (Irvine, USA)

Dorsolateral nigral hyperintensity on 1.5 versus 3T susceptibility-weighted magnetic resonance imaging in neurodegenerative parkinsonism

B. Heim, A. Grossauer, F. Krismer, W. Poewe, K. Seppi (Innsbruck, Austria)

Dynamic functional connectivity changes and striatal dopamine deficiency in Parkinson’s disease

A. Asendorf, H. Theis, M. Tittgemeyer, L. Timmermann, G. Fink, A. Drzezga, M. Hoenig, T. van Eimeren (Cologne, Germany)

EEG power-spectra parametrization and cognitive ability in Parkinson’s disease

R. Shoorangiz, N. Slater, G. Hall-Mcmaster, E. Peterson, L. Livingston, S. Grenfell, K. Clifford, A. Harris, I. Kirk, L. Tippett, R. Jones, T. Anderson, T. Melzer, J. Dalrymple-Alford (Christchurch, New Zealand)

Effect of exercise on brain metabolism and energetics in PD

C. Bevington, R. Jayde Williams, B. Pike, J. Mckenzie, J. Zhang, W. Luh, AJ. Stoessl, V. Sossi (Vancouver, Canada)

Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder

L. Lopes, P. Wu, J. Lu, J. Wang, C. Bassetti, A. Rominger, C. Zuo, H. Yu, K. Shi (Bern, Switzerland)

Gait abnormalities relate to increased extracellular water in the substantia nigra in Parkinson’s disease patients

M. Bange, G. Gonzalez-Escamilla, N. Lang, A. Radetz, H. Ding, D. Herz, W. Schöllhorn, M. Muthuraman, S. Groppa (Mainz, Germany)

Gray matter volume of proposed brain-first and body-first Parkinson’s disease subtypes

M. Banwinkler, V. Dzialas, M. Hoenig, T. van Eimeren (Cologne, Germany)

Gray matter volumetry, cortical thickness and cognitive performance in treated Parkinson’s disease with REM sleep behavior disorder symptomatology

J. Oltra, A. Campabadal, C. Uribe, J. Pardo, MJ. Marti, Y. Compta, F. Valldeoriola, N. Bargallo, A. Iranzo, C. Junque, B. Segura (Barcelona, Spain)

In vivo synaptic density in parkinsonism

C. Uribe, KL. Desmond, R. Raymond, K. Smart, A. Reilhac, A. Mena, AE. Lang, G. Kovacs, N. Vasdev, AP. Strafella (Toronto, Canada)

Intermediate cardiac denervation in early Parkinson’s disease

S-W. Yoo, J-S. Kim (Seoul, Republic of Korea)

Longitudinal Analysis of the Corticospinal Tract in Parkinson’s disease Patients

R. Guimaraes, L. Ramalho, B. Campos, F. Cendes (Campinas, Brazil)

Longitudinal combined 11C UCB J and 18F FE PE2I PET imaging of presynaptic terminal loss in early Parkinson’s disease.

A. Delva, K. van Laere, W. Vandenberghe (Leuven, Belgium)

Longitudinal study of Parkinson’s disease-related pattern with resting state functional MRI

A. Vo, N. Nguyen, D. Eidelberg (Manhasset, USA)

Longitudinal white matter microstructural changes in the prodromal phase of PD: A 2 year prospective study

A. Droby, A. Yoffe-Vasiliev, RM. Hutchison, S. Paz, J. Cedarbaum, N. Giladi, A. Mirelman, A. Thaler (Tel Aviv, Israel)

MIBG uptakes in the major salivary glands among Lewy body disease using a semi-automatic quantitative method

J. Ebina, S. Mizumura, N. Ishii, Y. Kobayashi, M. Shibukawa, J. Nagasawa, M. Yanagihashi, T. Hirayama, K. Kawabe, S. Orimo, O. Kano (Tokyo, Japan)

MRI biomarkers of freezing of gait development in in Parkinson’s disease

E. Sarasso, S. Basaia, C. Cividini, T. Stojkovic, I. Stankovic, N. Piramide, A. Tomic, V. Markovic, E. Stefanova, VS. Kostic, M. Filippi, F. Agosta (Milano, Italy)

MRI to investigate cerebrovascular changes in Parkinson’s disease

D. Nolan, D. Myall, C. Morgan, R. Shoorangiz, L. Livingston, S. Grenfell, T. Pitcher, M. Macaskill, K-L. Horne, C. Le Heron, S. Marsh, J. Dalrymple-Alford, T. Anderson, T. Melzr (Christchurch, New Zealand)

Multi-modal MRI features and their relationship with clinical scales in Parkinson disease and Atypical Parkinsonian Syndromes

H. Martinez-Hernandez, D. Lopez-Mena, B. Candela-Solano, A. Medina-Islas, L. Alvarez, I. Acosta (Mexico City, Mexico)

Multimodal assessment of nigrostriatal degeneration in de novo Parkinson’s disease

M. López-Aguirre, M. Matarazzo, J. Blesa, A. Sánchez-Ferro, M. Hm Monje, J. Obeso, J. Pineda-Pardo (Móstoles, Spain)

Multimodal mechanistic disease stratification in sporadic Parkinson’s disease

T. Payne, T. Burgess, M. Sassani, S. Roscoe, S. Bradley, A. Anton, E. Reed, I. Wilkinson, H. Mortiboys, T. Jenkins, O. Bandmann (Sheffield, United Kingdom)

Multimodal MRI assessment of the substantia nigra in premotor and motor stages of parkinsonism

J. Pasquini, MJ. Firbank, L. Best, V. Foster, V. Silani, G. Petrides, DJ. Brooks, KN. Anderson, N. Pavese (Newcastle upon Tyne, United Kingdom)

Neural correlates of Parkinson’s disease dysgraphia

L. Véron-Delor, M. Longcamp, JL. Anton, B. Nazarian, J. Sein, T. Witjas, S. Grimaldi, JP. Azulay, A. Eusebio, S. Pinto, J. Danna (Aix-en-Provence, France)

Neuroimaging in Glucocerebrosidase-associated parkinsonism: a systematic review

R. Balestrino, F. Agosta, S. Basaia, M. Filippi (Milano, Italy)

Nigral microvasculature imaging in Parkinson’s disease

S. Sharma, S. Buch, D. Reese, M. Haacke, M. Jog (London, Canada)

NODDI- based maps as potential marker for Parkinson’s Disease.

AP. Prabhu, S. Bhardwaj, A. Indoria, M. Gothwal, R. Yadav, PK. Pal, J. Saini (Bengaluru, India)

Non-dopaminergic system is related with motor reserve in Parkinson’s disease

J. Youn, JH. Won, M. Kim, SH. Moon, M. Kim, JH. Ahn, YE. Huh, H. Park, JW. Cho (Seoul, Republic of Korea)

Olfactory Network Reorganization in Parkinson’s Disease

L. Pesantez Pacheco, M. Saqib, D. Ehrlich, M. Hallett, S. Horovitz (Bethesda, USA)

Optimization of a neuromelanin MRI protocol for use in a longitudinal study of substantia nigra depigmentation in early Parkinson’s Disease (the InsIght-PD study)

T. Hayat, S. Pszczolkowski, Y. Xing, C. Tench, P. Morgan, J. Evans, D. Auer (Nottingham, United Kingdom)

Parkinson’s disease and nucleus basalis of Meynert integrity: Cognition and everyday function

N. Slater, R. Shoorangiz, G. Hall-Mcmaster, A. Harris, L. Livingston, S. Grenfell, K. Clifford, T. Anderson, T. Melzer, J. Dalrymle-Alford (Christchurch, New Zealand)

Patient-specific multivariate gray matter volumetric distance to predict disease severity in Parkinson’s disease

A. Vijayakumari, H. Fernandez, B. Walter (Cleveland, USA)

Patterns of early-phase 18F-FP-CIT PET images and the risk of dementia conversion in Parkinson’s disease

S. Chung, P. Lee, Y. Kim, Y. Sohn (Yongin-si, Republic of Korea)

Pedunculopontine Nucleus Structural Integrity and Freezing of Gait in Parkinson’s Disease Patients

K. Yen, R. Camicioli, M. Gee, F. Ba (Edmonton, Canada)

Prediction of early-stage Parkinson’s disease using connectivity and morphometry of the striatum

D. Henadeerage Don, E. Alushaj, N. Handfield-Jones4, A. Khan, P. Macdonald (London, Canada)

Quantity detection of Substantia nigra hyperechogenicity based on digital image analysis for diagnosing Parkinson’s disease

L. Gao, Z. Xue, X. Zhou (Nanchang, China)

Repetitive transcranial magnetic stimulation for hypokinetic dysarthria in PD enhances white matter integrity in the auditory-motor loop tract

I. Rektorova, L. Brabenec, M. Kostalova, A. Sejnoha-Minsterova (Brno, Czech Republic)

Subclinical cognitive patterns of caudate-anchored connectivity in early Parkinson’s disease

S-W. Yoo, J-S. Kim, K-S. Lee (Seoul, Republic of Korea)

Subcortical Atrophy and Fall Risk in Parkinson’s Disease

S. Aggarwal, J. Ma, M. Salgado, M. Hamed (Chicago, USA)

Temporal Dynamic Alterations of Regional Homogeneity in Parkinson’s disease: A Resting-State fMRI Study

T. Yuan, L. Kai, S. Wen (Beijing, China)

The brain-age framework in Parkinson’s disease: evaluating MRI morphometry and sex-dimorphism

G. Gonzalez-Escamilla, P. Farag, M. Bange, S. Groppa (Mainz, Germany)

The clinical challenge of an unilateral abnormal uptake in datscan

C. Silva, F. Barros, F. Matias, CM. Machado, FM. Moreira, M. Cunha, A. Morgadinho (Coimbra, Portugal)

The distinctive functional connectivity of the cholinergic nucleus basalis of Meynert in Parkinson’s disease across different motor subtypes

M. Nazmuddin, P. Zeidman, T. van Laar (Surabaya, Indonesia)

The effect of levodopa on speech in patients with Parkinson’s disease

M. Mrackova, R. Marecek, J. Mekyska, M. Kostalova, R. Rektorova (Brno, Czech Republic)

The functional neuroanatomy of cortical slowing predicts clinical features of Parkinson’s disease

A. Wiesman, E. Fon, S. Baillet (Montreal, Canada)

The noradrenergic basis of Parkinson’s tremor

A. Heide, M. Wessel, D. Papadopetraki, D. Geurts, T. van Prooije, F. Gommans, R. Helmich (Nijmegen, Netherlands)

The role of cortical and subcortical structures in maintaining efficient network topology in Parkinson’s disease

R. Berlot, B. Koritnik, Z. Pirtošek (Ljubljana, Slovenia)

Using quantitative susceptibility mapping and diffusion magnetic resonance imaging to identify structural features of early-stage Parkinson’s disease

E. Alushaj, D. Hemachandra, N. Handfield-Jones, A. Kuurstra, R. Menon, A. Owen, A. Khan, P. Macdonald (London, Canada)

Verifying imaging accuracy for targeting and lead positioning in DBS: a phantom study.

A. Rohaan, Y. Willems, N. Vander Gaag (Leiden, Netherlands)

White Matter Correlates of Physical Therapy Measures in Parkinson’s disease Patients with Freezing of Gait

V. Mishra, J. Longhurst, K. Sreenivasan, D. Cordes, A. Ritter, Z. Mari (Las Vegas, USA)

White Matter Perivascular Spaces in Parkinson’s Disease are Associated with Decreased Cognition, Interrupted Sleep, and Less Physical Activity

E. Donahue, S. Venkadesh, R. Foreman, J. Duran, V. Bui, D. Wing, A. Petkus, I. Litvan, E. Bayram, D. Schiehser, J. Choupan, M. Jakowec, G. Petzinger (Los Angeles, USA)

White matter structural network of motor reserve in early Parkinson’s disease

S. Chung, Y. Kim, C. Park, H. Shin, H. Lee, Y. Kim, M. Yun, P. Lee, Y. Sohn, Y. Jeong (Yongin-si, Republic of Korea)

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