Understanding the relationship between synaptic density and dopamine transporter availability in Parkinson’s disease
Objective: To evaluate how disease duration in PD affects the coupling of DAT (18F-FE-PE2I) and SV2A density (11C-UCB-J) in the nigrostriatal regions (where both tracers…Assessing the potential association of rs2298383 in ADORA2A as a predictor of Levodopa-Induced Dyskinesia in Latin American Parkinson’s Disease patients
Objective: To analyze the association between ADORA2A-rs2298383 and levodopa induced dyskinesias (LID) in a cohort of Latin American Parkinson’s disease patients. Background: Previous evidence has…Insights into Genetic Counseling Recall and Clinical Trial Interest in PD GENEration
Objective: To assess the impact of participation in PD GENEration, a large-scale genetic and counseling study for Parkinson’s disease (PD). We evaluated the recall of…Linking Adolescent Brain Development To Parkinson’s Disease Risk Using Machine Learning On Polygenic Risk Scores
Objective: Examine whether adolescent brain structural deviations contribute to Parkinson’s disease (PD) susceptibility. Background: Genetic variants associated with PD have been linked to neurodevelopmental processes,…Improving Recruitment of Black and African American Participants in Parkinson’s Genetics Research
Objective: To describe recruitment methods and lessons learned to date in the BLAAC PD study. Background: Diversity in Parkinson’s disease (PD) research is largely lacking.…The Role of Polygenic Background and APOE E4 in Monogenic and Idiopathic Parkinson’s Disease
Objective: To assess the impact of 1) polygenic risk scores (PRS) on monogenic Parkinson’s disease (PD) risk and time to diagnosis and 2) APOE E4…Magnetic Resonance Guided Focused Ultrasound for Essential Tremor and Tremor dominant Parkinson’s Disease Case Series
Objective: To assess the efficacy and safety of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) for Essential Tremor (ET) and Tremor Dominant Parkinson's Disease (TDPD) in…Minimally Invasive Magnetic Resonance Imaging guided Deep Brain Stimulation for Movement Disorders – A Novel technique, Accuracy and Clinical Outcome.
Objective: To study the accuracy of lead placement and clinical outcome of a novel technique using twist drill hole and smaller incision in Magnetic resonance…Full-year Open-label Tracking of Adaptive Deep Brain Stimulation in Parkinson’s Disease in Two Patients: Considerations for Long-term Algorithm Maintenance
Objective: To assess the effects of chronic adaptive deep brain stimulation (aDBS) on motor symptoms and quality of life (QoL) and algorithm stability in two…EEG Correlates of Orthostatic Hypotension in Parkinson’s Disease: Novel Biomarkers for Autonomic Failure
Objective: To identify potential EEG biomarkers associated with orthostatic hypotension in Parkinson Disease (PD) and evaluate their relationship with clinical measures of autonomic dysfunction. Background:…
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