LRRK2 Polymorphisms and Associations with Parkinson’s Disease in Participants of East Asian, Southeast Asian, and European Descent
Objective: To investigate the prevalence of LRRK2 polymorphisms, R1628P and G2019S, and their association with Parkinson’s Disease (PD) in cohorts of East Asian (EA), Southeast…Rare Variant Analysis of Sphingolipid-related Genes in Large Chinese Parkinson’ s Disease Cohorts
Objective: This study investigated the link between rare variants in sphingolipid-related genes and Parkinson’s disease (PD) in a Chinese mainland population. Background: Recently, growing evidence…Longitudinal Analysis of Disease Progression in GBA-Associated Early-Onset Parkinson’s Disease
Objective: This study aims to investigate the longitudinal disease progression of early-onset Parkinson’s disease (EOPD) in carriers of GBA mutations compared to genetically undefined EOPD…Monogenic Parkinson’s Disease patients in Central Europe within the CEGEMOD consortium
Objective: To report the genetic results of genotyping and whole-exome sequencing (WES) data of patients with Parkinson’s disease (PD) from the Central European countries of…Genetic risk modifiers for GBA1 carriers in Parkinson’s disease: from the Global Parkinson’s Genetics Program
Objective: To identify potential genetic risk modifiers for GBA1 variant carriers across genetically determined European ancestries (European, Ashkenazi Jewish, Finnish, and Icelandic) using data from…Digital Health Technology Demonstrates Efficacy of Algorithmic DBS Programming
Objective: To test the feasibility and performance of algorithmic image-guided programming for deep brain stimulation (DBS) using a digital health technology, Quantitative Digitography (QDG), as…Deep Brain Stimulation (DBS) Placement in a Patient with Parkinson’s disease (PD) and Polyostotic Fibrous Dysplasia (PFD)
Objective: To describe a patient who has PD and a history of PFD implanted with DBS. Background: PD is the second most common neurogenerative disorder…Efficacy of Unilateral Focused Ultrasound Subthalamotomy in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy of unilateral focused ultrasound subthalamotomy (FUS-STN) in treating patients with Parkinson’s Disease (PD). Background: PD is a neurodegenerative disorder with…Optimizing Electrode Placement in STN-DBS for Parkinson’s Disease: The Added Value of Intraoperative Neurophysiological Monitoring
Objective: This study aims to evaluate the role of intraoperative neurophysiological monitoring, specifically microelectrode recording (MER) and test stimulation, in optimizing electrode placement for deep…Novel Technologies for REM Sleep Behavior Disorder Detection to Identify Prodromal Parkinson’s Disease at Home
Objective: Isolated REM sleep behavior disorder (RBD) is a strong prodromal marker of Parkinson’s disease (PD) and related alpha-synucleinopathies. Early identification is crucial for timely…
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