MDS Virtual Congress 2020

September 12-16, 2020. Virtual Congress. www.mdscongress.org

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Saccadic and Smooth Pursuit Derangements in Essential Tremor: A Video Oculography Study

T. Sahin, R. Yilmaz, M.C Akbostanci (Ankara, Turkey)
Safety and efficacy of focused ultrasound staged bilateral thalamotomy for Essential tremor

R. Martinez-Fernandez, J. Pineda-Pardo, J. Mañez-Miró, M. del Álamo, F. Hernandez-Fernandez, R. Rodriguez-Rojas, L. Guida, M. Matarazzo, L. Hermes-Gonzalez, L. Diaz-Fernandez, C. Ammann, L. Vela, J. Obeso (Móstoles, Spain)
Safety and efficacy of istradefylline, an adenosine A2A receptor antagonist, as a function of baseline dyskinesia (BL-dyskinesia) in Parkinson’s disease (PD): A pooled analysis of 4 studies

L. Elmer, K. Toyama, J. Parno, D. Braccia, R. Ristuccia, A. Mori (Toledo, OH, USA)
Safety and Tolerability of Burst Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease

W. Hu, J. Wang, R. Barmore, J. Melo Lobo, T. Tsuboi, A. Wang, A. Ramirez-Zamora, M. Okun, L. Almeida (Gainesville, FL, USA)
Safety, Tolerability, and Pharmacodynamic Profile of DNL201 at dose levels demonstrating LRRK2 inhibition in Parkinson’s Disease Patients with and without LRRK2 mutations

D. Jennings, P. LeWitt, D. Kern, I. Goodman, A. Siderowf, O. Omidvar, A. Ellenbogen, J. Aldred, R. Macuica, S. Huntwork-Rodriguez, C. Ho, M. Troyer (South San Francisco, CA, USA)
Salivary proteome in Parkinson’s disease

M. Figura, A. Friedman (Warsaw, Poland)
Satisfaction and impact on quality of life in patients with essential tremor treated with High Intensity Focused Ultrasound (HIFU) thalamotomy

F. Hernandez-Fernandez, R. Martinez-Fernandez, J.U Mañez-Miro, P. Martinez-Martin, J.A Obeso (Móstoles, Spain)
Say “AH~”: Vocal Analysis in Parkinson’s Disease and Essential Tremor

J.E Park, S.W Oh, J.Y Shin, S.Y Lee, S.H Hong, N.H Ahn, H.J Kim, K.H Lee, J.E Bae, H.B Lee (Goyang, Republic of Korea)
SCA48: Ataxia Plus Chorea in a New Spanish Family

M.I Gastón, G. Soriano, A. Alonso, S. Pasalodos, J. Salgado, M. Mendioroz (Pamplona, Spain)
Screening of mutations in PARK2 gene and Dopamine levels in Parkinson’s disease (PD) patients in Coimbatore population, India

I. Iyer, V. Venkatesan, V. Vellingiri (Coimbatore, India)
Secondary Vascular Parkinsonism: Role of increasing levels cortisol in the cognitive impairment

D. Akramova (Tashkent, Uzbekistan)
Selective α-synuclein overexpression-induced pathology in noradrenergic neurons: a new mouse model for prodromal Parkinson’s disease?

B. Lee, Y. Chen, G. Ganjam, N. Decher, A. Gundlfinger, W.J Berg, M. Britschgi, O. Oertel (Marburg, Germany)
Self-perceived stigma and motor symptoms in patients with Parkinson’s disease

A. Kumon, M. Sagawa, M. Saruwatari, N. Kawashima, K. Hasegawa (Sagamihara, Japan)
Self-Perception of Dysphagia Before and After Botulinum Toxin Injection for Cervical Dystonia

A. Silbergleit, K. Hamilton, L. Schultz, J. Turnbull, E. Boettcher, R. Konnai, N. Patel, C. Sidiropoulos (West Bloomfield, MI, USA)
Sensitive biomarker of Parkinson’s disease linked to mutations in the glucocerebrosidase gene

S. Pchelina, M. Nikolaev, A. Kopytova, G. Baydakova, K. Senkevich, I. Miliukhina, T. Usenko, A. Emelyanov, E. Zakharova (St.Petersburg, Russian Federation)
Sensor-Based Gait Measurements Predict Subthalamic Deep Brain Stimulation Frequency in Parkinson’s Disease Patients – A Proof of Concept Study

J. Watts, A. Khojandi, O. Shylo, R. Ramdhani (Knoxville, TN, USA)
Sensorimotor inhibition relates to gait dysfunction in people with Parkinson’s disease

D. Martini, G. Harker, R. Morris, J. Nutt, F. Horak (Portland, OR, USA)
Sensory Trick in Oromandibular and Tongue Dystonia in Patient with Wilson’s Disease

C. Shambetova (Bishkek, Kyrgyzstan)
Serious games home rehabilitation program to treat gait and balance disorders in patients with Parkinson’s disease: A randomised controlled trial

D. Nuic, S. de Weijer, E. Zeeboer, C. Olivier, S. Cherif, P. Foulon, B.R Bloem, N. De Vries, M.L Welter (Paris, France)
Serum microRNA expression levels in Turkish patients with Parkinson’s disease

B. Ozdilek, B. Demircan (Istanbul, Turkey)
Serum microRNA-29 family as potential biomarkers for cognitive impairment in Parkinson’s disease

Y.L Tang, LL. Han, F. Huang, J. Wang (Shanghai, China)
Serum molecular markers and non-motor symptoms in Parkinson’s disease

I. González-Aramburu, M. Sierra, J. Infante, S. Jesús Maestre, M. Aguilar, P. Pastor, J. Hernández Vara, S. Escalante, F.J Carrillo Padilla, M. Pueyo, J.M García Moreno, V. Puente, A. Crespo Cuevas, O. de Fábregues-Boixar, B. Solano Vila, T. de Deus-Fonticoba, P. Martínez Martín, P. Mir, D. Santos García (Santander, Spain)
Serum neurofilament light chain differentiates early Parkinson’s disease from progressive supranuclear palsy-parkinsonism

R. Yadav, P. Ramaswamy, P. Pal, R. Christopher (Bengaluru, India)
Serum Neurofilament light chain levels and disability milestones in Lewy body diseases

A. Pilotto, A. Imarisio, F. Conforti, A. Lupini, G. Giannì, S. Gipponi, E. Cottini, A. Scalvini, S. Masciocchi, S. Nocivelli, R. Grasso, R. Turrone, B. Borroni, M. Rizzetti, L. Bonanni, M. Pizzi, A. Bellucci, E. Garraffa, H. Zetterberg, N. Ashton, A. Hye, A. Padovani (Brescia, Italy)
Severity of Motor Symptoms in Parkinson’s Disease in Kazakhstan (on the example of the city of Almaty)

A. Aralbayeva, S. Kamenova, A. Kondybaeva, K. Kuzhibaeva (Almaty, Kazakhstan)
Sex differences on dynamic functional connectivity in Parkinson’s disease and healthy controls

M. Diez-Cirarda, I. Gabilondo, N. Ibarretxe-Bilbao, J.C Gomez-Esteban, J. Kim, O. Lucas-Jimenez, R. Del Pino, J. Peña, N. Ojeda, A. Mihaescu, M. Valli, M.A Acera, A. Cabrera, M.A Gomez-Beldarrain, A.P Strafella (Toronto, ON, Canada)
Sex Moderates the Effects of Neurofibrillary Tangles on Cognition for Diffuse Lewy Body Pathology

E. Bayram, I. Litvan (La Jolla, CA, USA)
Sex-associated difference in the presentation and progression of Parkinson’s disease

H. Iwaki, C. Blauwendraat, M. Nalls, A. Singleton (Glen Echo, MD, USA)
Sex-related disease differences in Parkinson’s disease

P. Kohloff, M. Lubomski, L. Rushworth, R. Davis, C. Sue (Darlinghurst, Australia)
Sex-related longitudinal change of motor features and biological biomarkers in early Parkinson’s disease from the PPMI cohort

M. Picillo, S. Bressman, C. Coffey, N. Dahodwala, R. Sanders-Pullman, C. Tanner, A. Amara (Salerno, Italy)
Sex-specific neuroprotection by inhibition of the Y-chromosome gene, SRY, in experimental Parkinson’s disease

J. Lee, P. Pinares-Garcia, H. Loke, S. Ham, E. Vilain, V. Harley (Clayton, Australia)
Sex-specific white matter alterations in Parkinson’s disease with mild cognitive impairment

V. Mishra, K. Sreenivasan, D. Cordes, A. Ritter, Z. Mari, I. Litvan, J. Caldwell (Las Vegas, NV, USA)
Sexual Dysfunction Among Patients with Parkinson’s Disease in Dakar Senegal

H.D Ewodo, M. Traore, B.G Ekanmian, C.G De Chacus, K. Toure (Dakar, Senegal)
Sexual dysfunction associated with deep brain stimulation of the Globus Pallidus pars interna

T. Fay-Karmon, G. Bronner, S. Hassin-Baer, S. Israeli-Korn (Ramat-Gan, Israel)
Sexual dysfunction precedes the classical motor symptoms of Parkinson’s disease?

T. Uchiyama, T. Yamamoto, R. Sakakibara, K. Suzuki, T. Kadowaki, S. Kuwabara, K. Hirata, H. Murai (Chiba, Japan)
Shear wave sonoelastography is effective in detecting myofascial trigger points and spasticity

R. Bubnov, L. Kalika (Kyiv, Ukraine)
Short digitalized cognitive test help differentiating Parkinson’s disease (PD) patients with and without Mild Cognitive Impairment (MCI)

J. Montillot, H. Salhi, R. Massart, K. Hernandez, M. Lunven, G. Fénelon, A. Bachoud-Lévi, P. Rémy (Créteil, France)
Short- and Long-term Healthcare Resource Utilization in Parkinson’s Disease – 20 years of Follow Up in a Population-based Cohort

Y. Barer, N. Gavrielov, I. Goldshtein, M. Martinec, I. Korolev, P. Coloma (Tel Aviv, Israel)
Significant hypometabolism in the posterior parietal cortex and precuneus in Parkinson’s disease with GBA mutations: [18F]FDG PET study

C. Lee, K. Park, S. Kim, B. Lee (Seoul, Republic of Korea)
Simultaneous, levodopa-responsive Holmes’ tremor and hemiparkinsonism due to midbrain cavernous malformation

A. Dessy, P. Drummond (New York, NY, USA)
Single-energy Metal Artefact Reduction: a Precise Method for Localization of Deep Brain Stimulation Electrodes in Parkinson’s Patients

W. Xian, L. Chen, J. Liu, C. Yang (Guangzhou, China)
Site investigator perspectives on exclusionary determinations of SWEDDs (Scans Without Evidence of Dopaminergic Deficit) during screening in the SURE-PD3 study

G. Crotty, E. Macklin, A. Hung, M. Schwarzschild (Boston, MA, USA)
SLC20A2 mutation manifesting as very-late onset orofacial dyskinesia

K.A Woo, D. Yoo, B. Jeon, J.Y Lee (Seoul, Republic of Korea)
Sleep and Polysomnographic Abnormalities in Indian Patients with Huntington’s Disease

J. Annapureddy, S. D V, N. Kamble, P. Pal, S. Jain, B. Kutty, R. Yadav (Bangalore, India)
Sleep disturbances in Vascular Parkinsonism (VP) and Parkinson’s Disease (PD) patients in early stages

R. Raimundo, M. Mendes, R. Jesus, C. Azoia, A. Marques, A. Almeida, A. Velon (Vila Real, Portugal)
Sleep Disturbances in Young Onset Parkinson’s Disease

A. Patwardhan, P. Pal, N. Kamble, R. Yadav (Bangalore, India)
Sleep Patterns in Relation to Disease Severity in Parkinson’s Disease: A Study of 84 Ibadan Patients

R. Oguntoye (Ibadan, Nigeria)
Sleep-related Symptoms in Multiple System Atrophy: Determinants and Impact on disease severity

J.Y Lin, L.Y Zhang, B. Cao, QQ. Wei, H.F Shang (Chengdu, China)
Slow Motion Analysis of Repetitive Tapping (SMART) test: a new means to assess bradykinesia

C. Simonet, C. Lambert, R. Rees, M. Galmes, A. Schrag, A. Noyce (London, United Kingdom)
Smartphone applications in Parkinson’s disease: current data on disease monitoring, medication adherence, and movement modulation

S. Tripathi, A. Malhotra, S. Barkan, C. Henchcliffe, H. Sarva (New York City, NY, USA)
Smartphone-based context awareness to improve ambulatory Parkinson’s monitoring

A. Hadley, B. Walter, A. Espay, D. Heldman (Cleveland, OH, USA)
Smell and Taste in Blepharospasm

J. Gamain, T. Herr, T. Hummel, B. Veit, C. Willert, B. Lehnert, R. Fleischmann, A. Stenner, F. Tost, M. Kronenbürger (Greifswald, Germany)
SNCA hypomethylation in rapid eye movement sleep behavior disorder is a potential biomarker for Parkinson’s disease

A. Zhao, Y. Li, M. Niu, G. Li, L. Zhou, N. Luo, W. Kang, J. Liu (Shanghai, China)
SNPs in SNCA, MCCC1, DLG2, GBF1, and MBNL2 are associated with Parkinson’s disease in southern Chinese populations

A. Zhao, Y. Li, M. Niu, G. Li, N. Luo, L. Zhou, W. Kang, J. Liu (Shanghai, China)
Socio-economic determinants of diagnostic latency in Parkinson’s disease patients

P. Surathi, E. Feinstein (Newark, NJ, USA)
Somatosensory temporal discrimination threshold improves after unilateral HIFU subthalamotomy in asymmetrical PD

C.M Ordás, F. Alonso-Frech, M. Hernández González-Monje, R. Martínez-Fernández, J. Máñez-Miró, M. Del Álamo, J.A Obeso (Móstoles, Spain)
Spatiotemporal Changes in Substantia Nigra Neuromelanin Content from Prodromal to Clinical Parkinson’s Disease

E. Biondetti, R. Gaurav, L. Yahia-Cherif, G. Mangone, N. Pyatigorskaya, R. Valabrègue, C. Ewenczyk, M. Hutchison, C. François, J.C Corvol, M. Vidailhet, S. Lehéricy (Paris, France)
Speech biometrics can predict cerebellar dysfunction in multiple sclerosis

A. Vogel, G. Noffs, F. Boonstra, T. Perera, S. Kolbe, J. Stankovich, H. Butzkueven, A. Evans, A. der Walt (Melbourne, Australia)
Speech is a sensitive marker in premanifest Huntington’s disease: exploring acoustic, cognitive and fine motor performance

A. Vogel, J. Chan, Y. Lie, J. Stout (Melbourne, Australia)
Spinal Cord Stimulation Improves Gait velocity but Not Freezing Episodes in PD Patient with Prior GPi-DBS: A Case Report

L.B Wang, Y.X Pan, T. Wang, C-C. Zhang, D.Y Li (Shanghai, China)
Spinal Cord Stimulation on Parkinson’s disease: Continuous or intermittent stimulation?

R. Carra, J. Menezes, R. Magalhaes, I. Kayo, M. Teixeira, K. Duarte, D. Andrade, E. Barbosa, T. Capato, R. Cury (Sao Paulo, Brazil)
Spinocerebellar Ataxia Type 3 Presenting with Motor Neuron Disease

C. Jaques, J. Pedroso, A. Rocha, W. Pinto, A. Oliveira, O. Barsottini (São Paulo, Brazil)
Spontaneous smoking cessation in a parkinsonian patient treated with apomorphine pump

M. Auffret, C. Geny, A. Lees, M. Vérin (Rennes, France)
Spreading ɑ-synuclein pathology initiated from the sublaterodorsal tegmental nucleus models RBD followed by Parkinsonian phenotypes in mice

Y. Shen, W.B Yu, B. Shen, H. Dong, J. Zhao, Y. Fan, Y.F Yang, Y.M Sun, Y.L Tang, F.T Liu, JJ. Wu, B.G Xiao, H. Yu, J. Koprich, Z.L Huang, J. Wang (Shanghai, China)
Staircase sign for Atypical and Secondary parkinsonism

Y.S Oh, J.S Kim, D.Y Kwon, M.H Park, B.R Bloem (Seoul, Republic of Korea)
Stiff person syndrome and acethylcoline receptors ganglionic neuronal antibodies

J. Lester, J. Cojab, E. Klériga (Huixquilucan, Mexico)
Stiff-person spectrum disorders in Russia: a retrospective analysis of 20 cases

Y.u Seliverstov, M. Ginzberg, E. Melnik, V. Fominykh, A. Skalnaya, L. Brylev (Moscow, Russian Federation)
Stimulation induced dystypia after pallidal deep brain stimulation

J. Wong, M. Armstrong, L. Almeida, M. Okun, I. Malaty (Gainesville, FL, USA)
Stimulation parameters of subthalamic deep brain stimulation in dystonia: a systematic review

Y. Wang, C. Zhang, B. Sun, D. Li, Y. Wu (Shanghai, China)
Striatal neurodegeneration in the presymptomatic phase of X-linked Dystonia-Parkinsonism

H. Hanssen, M. Heldmann, J. Dy, J. Tantianpact, J. Steinhardt, A. Sprenger, A. Domingo, C. Reyes, R. Rosales, C. Klein, T. Münte, A. Westenberger, J. Oropilla, C. Diesta, N. Brüggemann (Luebeck, Germany)
Structural and microstructural pathology in early de novo Parkinson’s disease patients with depression: An MRI study

E. de Natale, H. Wilson, M. Politis (London, United Kingdom)
Study on the clinical features of Parkinson’s disease with probable rapid eye movement sleep behavior disorder

J. Liu, Y. Xiang, C. Wan, X. Yan, B. Tang, J. Guo (Changsha, Hunan, China)
Subacute cognitive decline after DBS in a patient with idiopathic delayed-onset edema

T. De Santis, S. Lalli, D. Calandrella, A. Cocco, M. Di Giovanni, P. Amami, A. Ampollini, F. Motta, E. Mailland, L. Politi, M. Egidi, A. Albanese (Rozzano, Italy)
Subclinical cardiac autonomic dysfunction in patients with Parkinson’s disease: A pilot study

T.N Sathyaprabha, G. Inbaraj, N. Kuravatti, M.R Rukmani, B.S Krishnaprasad, R. Ravi, K. Mrudula, P. John (Bangalore, India)
Subjective Cognitive Complaints in early Parkinson’s Disease patients with normal cognition are associated with affective symptoms

C.Y Chua, M.E Koh, N.Y Chia, S.E Ng, S.E Saffari, M.C Wen, R.Y Chen, X. Choi, D.L Heng, S.X Neo, K.Y Tay, W.L Au, E.K Tan, L.S Tan, Z. Xu (Singapore, Singapore)
Substantia nigra echogenicity as a predictor of drug withdrawal response in suspected drug-induced parkinsonism: a five year follow-up study

B. Baena Álvarez, R. Sainz Amo, F. Rodríguez Jorge, J. Gómez Corral, F.J Buisán Catevilla, N. García Barragán, I. Corral Corral, A. Felipe Mimbrera, M.C Matute Lozano, J. Masjuán Vallejo, J.C Martínez Castillo, J.L López-Sendón, A. Alonso Cánovas (Madrid, Spain)
Substantianigral involvement on Tc99mDaTSPECT-a novel and under recognised imaging finding in Parkinsonian Disorders

S. Siddiqui, C. Nagaraj, J. Saini, P. Singh, R. Yadav, P. Pal (Bengaluru, India)
Successful treatment of incessant purposeless groaning in Progressive Supranuclear Palsy with Pimozide

M. Matta, A. Panwar, N. Sawal (Chandigarh, India)
Sulpiride-induced Parkinsonism in Peptic Ulcer and Gastroesophageal Reflux Disease Patients: A Nationwide Population-Based Study

C.Y Wei, M.C Lin, W.M Kung (Changhua County, Taiwan)
Super-Responders to Opicapone Adjunct Treatment to Levodopa in Parkinson’s Disease Patients with Motor Fluctuations: Combined Post-Hoc Analysis of BIPARK-I and II

A. Antonini, W. Poewe, J. Ferreira, G. Ebersbach, H. Gama, J.F Rocha, D. Magalhães, P. Soares-da-Silva (Padova, Italy)
Survival in Parkinson’s Disease and Association with MAPT and APOE

S. Kola, S. Armasu, D. Weis, O. Ross, D. Maraganore, A. Hassan (Rochester, MN, USA)
Survival in restless legs syndrome: An eleven-year surveillance, community-based population study

E. Cubo, C. Collazo, C. Gallego-Nieto, M. Elizari-Roncal, T. Barroso-Pérez, A. Echavarria, S. Calvo, C. Marras (Burgos, Spain)
Sustained Improvement in Freezing of Gait (FOG) and Treatment Satisfaction at 12 months After Initiation of Carbidopa/Levodopa Enteral Suspension (CLES) in Advanced Parkinson’s Disease (APD) Patients in USA: Interim Results from the PROviDE Study

R. Pahwa, S. Isaacson, B. Bluett, P. Kandukuri, N. Gupta, Y. Jalundhwala, P. Kukreja, I. Pan, J. Aldred (North Chicago, IL, USA)
Symptomatic palatal tremor following cerebellar stroke – Clinical and neuroimaging features

S. Bhattad, S. Pandey (New Delhi, India)
SYNGAP1-related intellectual disability with ataxia and late onset of epileptic seizures

N. Gogatishvili, T. Tkemaladze, V. Skrahina, S. Kasradze, A. Rolfs (Tbilisi, Georgia)

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