MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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MDS Virtual Congress 2020

September 12-16, 2020. Virtual Congress. www.mdscongress.org

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  • A brain signature of prodromal Lewy body dementia

    S. Rahayel, R. Postuma, J. Montplaisir, B. Mišić, C. Tremblay, C. Yao, M. Gaubert, J. Carrier, O. Monchi, F. Blanc, S. Chouinard, M. Panisset, A. Dagher, J.F Gagnon (Montreal, QC, Canada)

  • A C12orf65 mutation-related autosomal recessive hereditary spastic paraplegia is associated with autophagy induction

    L. Wu, Y. Xu, Q. Wang, X. Lai, I. Vinnikov, W. Chen (shanghai, China)

  • A case of cervical dystonia resulting from Vim-DBS surgery that was then responsive to stimulation: quantitative analysis of therapeutic effect on both fixed dystonic posture and dystonic tremor

    X. Mason, K. Cross, A. Wu, A. Arac, Y. Bordelon (Los Angeles, CA, USA)

  • A Case of Disabling Orofacial Dyskinesias Caused by Lupus Anticoagulant

    K. Colletta, S. Kletzel (Hines, IL, USA)

  • A case of generalized early-onset dystonia with a novel low-penetrant THAP1 missense variant

    I. Keller Sarmiento, A. Fraint, L. Kinsley, S. Lubbe, N. Mencacci, T. Simuni, D. Krainc (Chicago, IL, USA)

  • A Case of Hemiballism Associated with Temporal Lobe Infarction

    B. Crispin, E. Mattos, R. Suarez, Y. Nuñez, C. Cosentino (Lima, Peru)

  • A Case of Improved Psychotic Depression and Motor Symptoms in Parkinson’s Disease following Electroconvulsive Therapy (ECT)

    S. Ramesh, J. Ratliff (Philadelphia, PA, USA)

  • A Case of Lance Adams Syndrome with See-Saw Nystagmus

    G. Keeton, T. Ali, P. Sudhakar, Z. Guduru (Lexington, KY, USA)

  • A case report of myoclonus-dystonia with isolated myoclonus phenotype and novel mutation successfully treated with deep brain stimulation

    V. Besa Lehmann, M. Rosenbaum, L. Verhagen Metman (Santiago, Chile)

  • A Case Report of Spinocerebellar ataxia 13 with Parkinsonism

    A. Singh, L. Wu (Galveston, TX, USA)

  • A Case Series Highlighting Non-Traditional Movement Disorder Candidates for Deep Brain Stimulation Therapy Who Benefited Positively

    K. Oelerich, M. Afshari, A. Amin, G. Pal (Chicago, IL, USA)

  • A day in the life of Parkinson’s: Using passive monitoring to characterize the disease at home

    C. Tarolli, Z. Kabelac, T. Myers, E. Waddell, H. Rahul, R. Hristov, P. Auinger, T. Nordahl, E.R Dorsey, T. Ellis, D. Katabi (Rochester, NY, USA)

  • A Discrete-Choice Experiment Evaluating Preferences for On-Demand Treatments for Patients with Parkinson’s Disease and “OFF” Episodes

    A. Thach, J. Sutphin, J. Coulter, C. Mansfield (Marlborough, MA, USA)

  • A Fluctuating Qualitative Dermatoglyphic Trait, Dankmeijer’s and Furuhata’s Index as a Risk Marker in Diabetic Parkinson’s Patients of Guyana: A Case-Control Study

    A. Jha, S. D'costa, W. White, M. Chapp, D. Kanhai (Managua, Nicaragua)

  • A Korean first case of Boucher-Neuhäuser syndrome with two novel mutations of PNPLA6 gene

    E. Chung, S. Kim (Busan, Republic of Korea)

  • A large-scale full GBA1 gene screening in Parkinson’s disease in the Netherlands: 18 novel and 1 ‘Dutch’ variant

    J. den Heijer, V. Cullen, M. Quadri, A. Schmitz, D. Hilt, P. Lansbury, H. Berendse, W. de Berg, R. de Bie, J. Boertien, A. Boon, M. Contarino, J. van Hilten, J. Hoff, T. van Mierlo, A. Munts, A. der Plas, M. Ponsen, F. Baas, D. Majoor-Krakauer, V. Bonifati, T. van Laar, G.J Groeneveld (Leiden, Netherlands)

  • A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in De Novo vs Rollover Patients With Parkinson’s Disease: Interim Results

    R. Pahwa, S. Fox, C. Singer, P. Bhargava, B. Navia (Kansas City, KS, USA)

  • A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Interim Results

    S. Factor, W. Ondo, S. Isaacson, P. Bhargava, B. Navia (Atlanta, GA, USA)

  • A longitudinal PET study to assess the state of microglia activation in a Phase 2 study of Laquinimod as a treatment for Huntington’s disease (LEGATO-HD)

    A.A Roussakis, M. Gennaro, M.F Gordon, R. Reilmann, B. Borowsky, G. Rynkowski, J.M Savola, M.R Hayden, R. Gunn, S. Tabrizi, P. Piccini (London, United Kingdom)

  • A longitudinal study on alpha-synuclein in plasma neuronal exosomes as a biomarker for Parkinson’s disease development and progression

    M. Niu, Y. Li, G. Li, L. Zhou, N. Luo, M. Yao, W. Kang, J. Liu (Shanghai, China)

  • A monocentric experience of Apomorphine pump follow-up on PD patients: The Optipump Cohort

    C. Virbel-Fleischman, M. Houot, Y. Rétory, S. Hardy, J.C Corvol, D. Grabli (Gentilly, France)

  • A New Complex dystonic presentation of a rare gene – CACNA1B and its response to Levodopa

    S. Medarametla, B. Nataraju, S. Kodapala, S. Raju (Bangalore, India)

  • A New Web-Based Tapping Test for Measuring Distal Bradykinesia in Parkinson’s Disease

    N. Akram, H. Li, A. Ben-Joseph, C. Budu, D. Gallagher, A. Noyce, C. Simonet (London, United Kingdom)

  • A Novel CACNA1A Nonsense Variant [c.6481C>G; (p.Arg2161Gly)] Causing Spino Cerebellar Ataxia Type 6 (SCA6)

    J.P Romero, J. Herreros, S. Santillán, Y. Moreno, A. Andújar (Madrid, Spain)

  • A Novel Case of Persistent Segmental Spinal Myoclonus Due to Spinal Astrocytoma Temporarily Relieved by Diversion of Cerebrovascular Fluid

    Y. Huang, A. Chuang (Taoyuan, Taiwan)

  • A novel easily performed objective test of fine motor skill in handwriting and drawing to support diagnosing Parkinson’s disease

    R. Zietsma, S. Bojic, A. Karki, R. Bauer, M. van Gils, L. Cluitmans, A. Tolonen, R. Walker, K. Gray (Edinburgh, United Kingdom)

  • A novel likely pathogenic SNCA variant associated with Parkinson’s disease

    B. Minafra, G. Buongarzone, S. Gana, M.L Valente, I. Palmieri, T. Biagini, M. Plumari, M. Avenali, R. Zangaglia, T. Mazza, C. Cereda, C. Pacchetti, E.M Valente (Pavia, Italy)

  • A novel peptide reduces α-synuclein levels and neurodegeneration in cell, invertebrate, and mammalian models of Parkinson’s disease

    D. O'Hara, S. Nim, K. Hall, M. Kapadia, M. De Snoo, H. Chau, S. Ngana, C. Corbi-Verge, A. Perez-Riba, S. Kalia, L. Kalia, P. Kim (Toronto, ON, Canada)

  • A novel phasic and restricted basal ganglia thalamocortical subcircuitry model

    D. Kumbhare, G. Weistroffer, M. Baron (Richmond, VA, USA)

  • A novel POLG2 variant leads to disrupted mitochondrial integrity in a family with cerebellar ataxia and progressive ophthalmoplegia

    K. Lohmann, M. Borsche, H. Baumann, S. Tunc, E. Knappe, S. Özcakir, J. Trinh, M. Dulovic-Mahlow, N. Brüggemann (Luebeck, Germany)

  • A Novel Variant of TUBB4A Dystonia (DYT4): A Case Report

    T. Lee, C. Goldin, D. Kern (Aurora, CO, USA)

  • A Parkinson’s disease (PD) case with underlying cerebral small vessel disease (CSVD)

    L.X Cao, W. Dong, Y. Li, G. Du, J.H Yin, Q. Yang, Y.Q Zhang, B. Chen, Y. Huang (Beijing, China)

  • A Parkinson’s disease dog providing therapeutic intervention in Parkinson’s disease

    C. Buckley, B. O'Callaghan, J. Dowler, N. Austin, E. Reynolds, M. Lowery, T. Lynch (Dublin 7, Ireland)

  • A Patient with Gait Disturbance Caused by Parkinson’s Disease: A Case Report

    M. Park, SS. Park, S.H Lee, C.Y Kim, I.W Choi, I.C Chae, H.R Yoo (Daejeon, Republic of Korea)

  • A pilot study on the efficacy, tolerability and safety of safinamide in elderly Parkinson’s disease patients

    D. Rinaldi, M. Sforza, E. Bianchini, S. Galli, F.E Pontieri (Rome, Italy)

  • A pilot study on the shift from rasagiline to safinamide in fluctuating Parkinson’s disease patients

    M.S Sforza, F.E Pontieri, D.R Rinaldi, E.B Bianchini (Rome, Italy)

  • A pooled analysis of four pivotal, randomized controlled trials of istradefylline, an adenosine A2A receptor antagonist: Efficacy as adjunct to levodopa in Parkinson’s disease (PD)

    C. Waters, R. Hauser, K. Toyama, J. Parno, D. Braccia, R. Ristuccia, A. Mori (New York, NY, USA)

  • A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AKST4290 in Subjects with Parkinson’s Disease on Stable Dopaminergic Treatment (TEAL Study)

    E. Rawner, J. Powell, S. Minami, K. Tang, V. Klutzaritz, E. McCaskill Newman, J. Hannestad (San Carlos, CA, USA)

  • A randomized, sham-controlled, crossover trial on Cerebello-Spinal Transcranial pulsed current stimulation (tPCS) in Ataxia

    J. Ganguly, D. Kulshreshtha, S. Soltani, Y. Krishnasamy Tamilselvam, O. Samotus, D. Aur, M. Jog (London, ON, Canada)

  • A Rare Disease with Atypical Clinical And Imaging Findings: Anti Lgi-1 Encephalitis

    O. Yilmaz Kusbeci, I. Keskin, M. Gedizlioglu (Izmir, Turkey)

  • A reliable measure of rigidity with a novel robotic device

    L. Caranzano, J. Madrid, F. Feurestein, T. Nef, D. Benninger (Lausanne, Switzerland)

  • A retrospective analysis of multicenter brain signal data recorded in Parkinson’s subjects implanted with deep brain stimulation leads

    M. Case, H. Bronte-Stewart, A. Kuhn, K. Botzel, A. Hebb, P. Starr, B. Klassen, N. Ince, Z. Blumenfeld, J. Neumann, F. Hell, S. Hanrahan, N. Swann, M. Ozturk, S. Stanslaski, S. Goetz, T. Denison, K. Bhatia, R. Raike (Fridley, MN, USA)

  • A sensor-based analysis of freezing of turning in bed: A new manifestation of nocturnal hypokinesia

    J. Sringean, C. Anan, C. Thanawattano, R. Bhidayasiri (Bangkok, Thailand)

  • A study of gut microbiota dynamics in Parkinsonian mice

    E. Klann, M. Tagliamonte, M. Ukhanova, V. Mai, V. Vedam-Mai (Gainesville, FL, USA)

  • A Systematic Review of the Psychometric Properties of Psychosis Rating Scales in Neurodegenerative Conditions

    P.S Malhotra, Y.M Wan, E.K Tan (London, United Kingdom)

  • A tailored and multifactorial fall prevention program for people with Parkinson’s disease: a feasibility study

    N. Allen, L. Clemson, C. Sherrington, S. Lewis, J. Close, S. Lord, S. Paul, S. Singh, C. Canning (Sydney, Australia)

  • A translational approach to determine target concentrations of MIN-102 (leriglitazone) to support a Phase II study in Friedreich’s ataxia

    S. Poli, L. Rodríguez-Pascau, J. Ros, P. González-Cabo, E. Britti, D. Lynch, G. Pina, S. Pascual, M. Cerrada-Gimenez, D. Eckland, E. Traver, J. Wetering-de-Rooij, M. Martinell, U. Meya, P. Pizcueta (Gosselies, Belgium)

  • A video self-modelling virtual reality intervention for freezing of gait in Parkinson’s disease: Preliminary findings from a pilot trial

    L. Goh, N. Ahmadpour, N. Allen, L. Clemson, E. Gorgon, S. Lewis, H. MacDougall, K. Ehgoetz Martens, J. Song, C. Canning (Lidcombe, Australia)

  • A Virtual Speech Therapist for Parkinson’s Disease

    A. Halpern, L. Ramig, R. Cole (Denver, CO, USA)

  • A Young Patient with Paroxysmal Choreoathetosis

    D. Di Luca, A. Milesi-Halle (Miami, FL, USA)

  • AADC gene therapy administered via a posterior approach: 18-month results from the PD-1102 trial in advanced Parkinson’s disease

    S. Factor, A. Van Laar, R. Richardson, C. Christine, P. Larson, S. Kostyk, R. Lonser, C. Li, G. Liang, A. Meier, E. Fine, R. Gross (Atlanta, GA, USA)

  • Aberrant resting-state functional connectivity in cognitively unimpaired patients with Parkinson´s disease and freezing of gait

    A. Martin-Bastida, M. Delgado-Alvarado, I. Navalpotro-Gomez, C. Caballero-Gaudes, M. Carreiras, M. Rodriguez-Oroz (Pamplona, Spain)

  • Abnormal Cerebral Glucose Metabolism and Dopaminergic Dysfunction in Patients with Parkinson’s Disease with Bilateral Onset

    P. Wu, L. Li, J. Lu, Q. Shi, Y. Zhu, J. Xiao, C. Zuo (Shanghai, China)

  • Abnormal network interconnections dynamics correlate with levodopa-induced dyskinesia in Parkinson’s disease

    Q. Si, Y. Yuan, C. Gan, M. Wang, L. Wang, K. Ma, K. Zhang (Nanjing, China)

  • Abnormal pattern of brain glucose metabolism in multiple system atrophy

    G. Martí-Andrés, M. Perovnik, E. Rebec, P. Tomše, E. Prieto, T. Rus, L. Armengou-García, L. Ležaić, M. Riverol, R. Valentí, M.R Luquin, M. Trošt, J. Arbizu (Pamplona, Spain)

  • Abrogation of neuroinflammation and behavioural deficit by Chlorogenic acid and Tinosporia cordiofolia in MPTP-Induced Parkinsonian mice model via suppressing NF-κB pathway

    D. Singh, M. Singh (Allahabad, India)

  • Accounting for unmeasured confounders in treatment response: a comparison of levodopa versus non-levodopa dopaminergic drugs

    M. Javidnia, W. Artman, J. Jones, A. Ertefaie, C. Venuto (Rochester, NY, USA)

  • Aceruloplasminemia Presenting as Huntington’s Disease –Look –Alike with Unique MRI Features

    S. Patil, M. Bhatt, A. Aggarwal (Andheri, Mumbai, India)

  • Activated microglia contribute to MPTP-induced impairment of cardiovascular function

    X. Liu, B. Wei, Q. Sun, Q. Bi, X. Shen, P. Shi (Hangzhou, China)

  • Acute Medically Refractory Hemichorea-Hemiballismus Treated by Unilateral Pallidotomy: A Case Report

    A. Brown, W. Jermakowicz, P. Konrad, P. Hedera (Nashville, TN, USA)

  • ADAM10 polymorphisms are not associated with susceptibility to Parkinson’s disease and Parkinson’s disease with cognitive impairment in a Chinese cohort

    P. Zhang, Y. Li, L.J Wang, Y.H Zhang (Guangzhou, China)

  • Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease: ADAPT-PD Trial: A Prospective Single-Blind, Randomized Crossover, Multi-Center Trial of Deep Brain Stimulation Adaptive Algorithms in Subjects with Parkinson’s Disease

    A. Kuhn, L. Tonder, R. Raike, S. Stanslaski, K. Lynch, H. Bronte-Stewart (Berlin, Germany)

  • Adaptive vs Conventional deep brain stimulation for Parkinson’s disease: a eight-hours study

    S. Marceglia, M. Prenassi, M. Arlotti, R. Ferrucci, L. Borellini, T. Bocci, F. Cogiamanian, M. Locatelli, S. Barbieri, A. Priori (Trieste, Italy)

  • Adrenoleukodystrophy Spastic Gait: Treatment with Fampridine

    E. Gisbert Tijeras, N. López Aríztegui, M.I Morales Casado, F. Muñoz Escudero, A. Fernández, N. García Alvarado, Á. Jamilena López, A. Fernández-Corada (Toledo, Spain)

  • Adult onset of Dandy-Walker Syndrome

    J. Sinelli, I. Cristea, C. Toader, N. Paun (Bucharest, Romania)

  • Advance Care Planning in Complex Stage Parkinson’s Disease

    M. Khwaja, A. Chatterjee, H. Avery, C. James (Reading, United Kingdom)

  • Advance Care Planning in Parkinson’s Disease – Are we getting it right?

    C. Grose, C. Thomas, B. Mohamed, R. Patten (Cardiff, United Kingdom)

  • Age and gender differences in cardiovascular autonomic failure in transgenic PLP-syn mouse model of multiple system atrophy

    M. Kermorgant, D. Arvanitis, P.O Fernagut, W. Meissner, J.M Senard, C. Galès, A. Pavy-Le Traon (Toulouse, France)

  • Age at onset and Parkinson’s disease progression

    G. D'Urso, K. Taylor, T. Kustermann, N. Pavese, G. Pagano (Basel, Switzerland)

  • Age-dependent expression of α-synuclein and its modification in non-neurodegenerative intestinal tract

    L. Bu, K. Huang, Y. Liang, S. Peng, Y. Chen (Guangzhou, China)

  • Agreement Between Neurologists on UPDRS Scoring and Symptom Laterality

    E. Smith, J. Bertoni, D. Bhatti (Omaha, NE, USA)

  • Alexithymia is associated with worse quality of life and caregiver burden in people with Parkinson’s disease

    M. Klietz, T. Schnur, S.C Drexel, F. Lange, L. Paracka, D. Dressler, G.U Höglinger, F. Wegner (Hannover, Germany)

  • Alexithymia, Depression, and Cognition in Patients with Parkinson’s disease

    G. Kenangil, M. Demir, E. Tur, F. Domaç (Istanbul, Turkey)

  • All-cause mortality in pimavanserin and atypical antipsychotic users with Parkinson’s disease in Medicare

    A. Mosholder, Y. Ma, S. Akhtar, G. Podskalny, Y. Wei, J. Liao, Y. Feng, H. Lyu, M. Wernecke, K. Leishear, L. Nelson, T. MaCurdy, J. Kelman, D. Graham (Silver Spring, MD, USA)

  • Allied health interventions for freezing of gait in Parkinson’s disease: a protocol for a systematic review and meta-analyses

    L. Goh, N. Allen, J. Song, L. Clemson, C. Canning (Lidcombe, Australia)

  • Allogeneic bone marrow-derived mesenchymal stem cells safety and tolerability in idiopathic Parkinson’s disease

    M. Schiess, J. Suescun, M. Doursout, C. Adams, C. Green, J. Saltarrelli, S. Savitz, T. Ellmore (Houston, TX, USA)

  • Alpha synuclein BAC transgenic mice as a preclinical model for disease-modifying therapies in Parkinson’s disease

    H. Yamakado, S. Okuda, T. Taguchi, M. Ikuno, M. Uemura, N. Uemura, M. Hondo, M. Yanagisawa, R. Takahashi (Kyoto, Japan)

  • Alpha-synuclein and Amyloid beta peptide 1-42 in Parkinson’s disease and parkinsonian plus syndrome cohorts

    G. Babu, M. Gupta, V. Paliwal (Lucknow, India)

  • Alpha-synuclein DNA methylation in CD45+ blood cells in Parkinson’s disease

    A. Lavrinova, N. Melnikova, A. Dmitriev, I. Miliukhina, E. Litusova, P. Gagarina, O. Berkovich, S. Pchelina, A. Emelyanov (Gatchina, Russian Federation)

  • Alpha-synuclein preformed fibril (PFF)-triggered synucleinopathy recapitulates neurochemical features of human PD: A PET study in rats

    C. Sortwell, J. Patterson, C. Kemp, K. Miller, A. Stoll, M. Duffy, K. Luk, V. Sossi (Grand Rapids, MI, USA)

  • Alterations in functional networks contribute to depression in Parkinson’s disease: A resting-state functional magnetic resonance imaging study

    Y. Qiu, L. Wang (Guangzhou, China)

  • Altered interhemispheric synchrony in Parkinson’s disease patients with levodopa-induced dyskinesias

    C.T Gan, M. Wang, QQ. Si, Y.S Yuan, Y. Zhi, L.N Wang, K.W Ma (Nanjing, China)

  • Altered metabolic and functional resting state activity in cognitively unimpaired and impaired Parkinson’s disease patients

    M. Ruppert, A. Greuel, M. Tahmasian, K. Steidel, F. Maier, J. Hammes, T. van Eimeren, L. Timmermann, M. Tittgemeyer, A. Drzezga, C. Eggers (Marburg, Germany)

  • Altered perceptual hand maps in focal hand dystonia

    T. Mainka, B. Ossmann, K. Zeuner, A. Baumann, T. Bäumer, A. Kühn, E. Azanon Gracia, S. Zittel, M. Longo, C. Ganos (Berlin, Germany)

  • Altered Spontaneous Brain Activity in Essential Tremor with and without Resting Tremor: A Resting-state fMRI Study

    L.Y Li, S.L Suo, L.N Li, L.D Lei, L.J Lu, W.L Wang, P.X Peng, D.R Duan, X.J Xi, J.Y Jiang, G.Y Gong, P.R Peng (Chengdu, Sichuan, China)

  • Amantadine Therapy for Ataxia Management in Patients with Spinocerebellar Ataxia Type 7

    L. Pesantez Pacheco, N. Thakur (Houston, TX, USA)

  • Amantadine-induced negative myoclonus in a patient with Parkinson’s disease: A case report

    M. Vuong, L. Poon, A. Lee, J.R Zuzuárregui (San Francisco, CA, USA)

  • Ambulatory Capacity Measure derived from the Movement Disorders Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)

    C. Venuto, G. Smith, R. Zielinski, M. Javidnia, T. Simuni, K. Kieburtz (Rochester, NY, USA)

  • Ambulosono: A Novel Sensor-based System for Quantitative Evaluation Freezing of Gait in Parkinson’s disease

    W. Xian, B. Hu, L. Chen, Z. Pei (Guangzhou, China)

  • Among Parkinson’s disease patients with both OFF and dyskinesia, ADS-5102 (amantadine) extended-release reduces disruptive motor episodes and improves function: Analysis of phase 3 trials

    R.A Hauser, D. Chernick, A. Formella (Tampa, FL, USA)

  • Amplitude training in Parkinson’s disease: Improved dressing independence

    K. Arnott, V. Campbell (Brisbane, Australia)

  • Ampreloxetine (TD-9855), a long-acting, norepinephrine reuptake inhibitor (NRI) for the treatment of neurogenic orthostatic hypotension (nOH) in subjects with synucleinopathies: Phase 3 clinical program

    L. Norcliffe-Kaufmann, C. Shibao, I. Biaggioni, H. Kaufmann, W. Wang, R. Vickery, B. Haumann (New York, NY, USA)

  • An aberrant embouchure dystonia network predicts objective and functional measures of severity

    A. Morris, S. Norris, B. Adeyemo, S. Petersen, A. Snyder, J. Perlmutter, J. Mink (Rochester, NY, USA)

  • An agent-based model replicates the pathogenic spread of alpha-synuclein in mice

    S. Rahayel, B. Mišić, Y.Q Zheng, Z.Q Liu, A. Caputo, K. Luk, A. Dagher (Montreal, QC, Canada)

  • An Analysis of Health Care Utilization in Functional Movement Disorders: Does Diagnosis Make a Difference?

    K. Kyle, A. Wu, F. Agosta (Los Angeles, CA, USA)

  • An Analysis of Parkinson’s Disease Medication Treatment Patterns among Medicaid Patients

    M. Johnsrud, K. Richards, R. Sasane, M. Leoni, S. Arcona (Austin, TX, USA)

  • An Apparent Cluster of Parkinson’s Disease (PD) in a Golf Community

    J. Nutt, A. Zajack, J. Sandsness, V. Palmer, C. Meng, C. Tanner, P. Spencer (Portland, OR, USA)

  • An introduction to the Global Parkinson’s Genetics Program (GP2)

    C. Blauwendraat, E. Riley, A. Singleton (Bethesda, MD, USA)

  • An investigation of the relationships between measures of pain, physical activity levels, sleep quality and mood in people with Parkinson’s disease

    V. Nguy, B. Barry, N. Moloney, L. Hassett, C. Canning, S. Lewis, N. Allen (Sydney, Australia)

  • An objective comparison of forward and backward postural instability in early Parkinson’s disease

    C. Lu, S. Amundsen Huffmaster, K. Louie, R. McGovern, C. MacKinnon, S. Cooper, R. Lowe, J. Vitek, R. Abulu (Minneapolis, MN, USA)

  • An Objective Tool to Guide Target Selection for DBS in PD (GPi vs STN)- integration into Thomas Jefferson’s multidisciplinary Movement Disorders Center, an Update

    R. Burke, L. Meytin, D. Kremens, J. Ratliff, A. Sharan, C. Wu, T. Liang (Philadelphia, PA, USA)

  • An Observational Study for the Application of Wearable, Multi-Sensor Technology to Characterize Motor Function of Parkinson’s Disease Patients in Japan (SWJ-001): An Innovative Protocol

    G. Oyama, T. Hatano, W.J Marks, R. Kapur, J. Fernandez, K. Fujikawa, T. Ogawa, H. Kamo, Y. Oji, H. Takeshige-Amano, D. Taniguchi, R. Nakamura, F. Sasaki, S. Ueno, N. Hattori (Tokyo, Japan)

  • An Observational Study for the Application of Wearable, Multi-Sensor Technology to Characterize Motor Function of Parkinson’s disease Patients in Japan (SWJ-001): Device Adherence

    T. Hatano, G. Oyama, J. Fernandez, K. Fujikawa, W.J Marks, R. Kapur, T. Ogawa, H. Kamo, Y. Oji, H. Takeshige-Amano, D. Taniguchi, R. Nakamura, F. Sasaki, S. Ueno, N. Hattori (Tokyo, Japan)

  • An Open-Label, Phase 1b Study of the Neuroactive Steroid GABAA Receptor Positive Allosteric Modulator SAGE-324 in Essential Tremor

    H. Colquhoun, D. Nguyen, M. Qin, A. Wehr, J. Doherty, S. Kanes (Cambridge, MA, USA)

  • An overview of vestibular function in Parkinson’s disease

    K. Hawkins, S. Paul, E. Chiarovano, I. Curthoys (Sydney, Australia)

  • An uncommon clinical phenotype associated with ANO10 mutation

    D. Silva, L. Guedes, A. Caldas (Torres Vedras, Portugal)

  • An unusual phenotype of spinocerebellar ataxia type 12

    K. Neeraja, V. Holla, S. Prasad, N. Kamble, R. Yadav, P. Pal (Bengaluru, India)

  • Analysing an extension type of Parkinson’s disease

    R. Kikuchi, T. Okamoto, S. Akaike, M. Miller, M. Kawamura (Yokohama, Japan)

  • Analysis of cases with Huntington’s disease phenotype and negative genetic test for huntingtin mutations in the Center for Movement Disorders (CETRAM) in Chile

    P. Salles, O. Benavides, N. Rojas, E. Solis, F. Canals, C. Kunstmann, L. Hudson, P. Saffie, J.M Fernandez, M. Terán, F. Vial, P. Chaná (Santiago, Chile)

  • Analysis of pupillometer results according to motor symptoms severity in Parkinson’s disease patients

    S. You, J. Yoo (Daegu, Republic of Korea)

  • Anatomy-guided injections of Botulinum neurotoxin in neck muscles: how accurate is needle placement?

    A. Kreisler, C. Simonin, A. Degardin, E. Mutez, L. Defebvre (Lille, France)

  • Andrograholide protect microglial activation via inhibiting mitochondrial ROS generation and NLRP3 inflammasome activation in in-vitro and in-vivo model of Parkinson’s disease

    S. Ahmed, V. Naidu (Kamrup, India)

  • Anti-parkinson effect of natural L-DOPA containing drug Mucuna pruriens against the rotenone induced rat model of Parkinson’s disease

    V. Kumar, F. Anwar (Allahabad, India)

  • Anticholinergic Burden in Parkinson’s Disease Patients in India – A Hospital Based Study

    A. Saini, R. Rajan, R. Anandapadmanabhan, V. Venogopalan, A. Gupta, B. Verma, N. Choudhary, R. Bhatia, M. Singh, A. Srivastava, P. Srivastava (New Delhi, India)

  • Anticholinergic Use in Parkinson’s Disease: Practice Patterns in Patients with Cognitive Impairment

    N. Shetty, O. Dubaz, Y. Yu, H. Gao, T. Simuni (Chicago, IL, USA)

  • Anxiety disorders are associated with verbal memory impairment in Parkinson’s disease

    N. Dissanayaka, E. Forbes, J. Yang, J. O'Sullivan, D. Copland, K. McMahon, L. Mitchell, G. Byrne (Brisbane, Australia)

  • Anxiety in Parkinson’s disease is associated with changes in the brain fear circuit

    G. Carey, R. Lopes, R. Viard, N. Betrouni, G. Kuchcinski, Q. Devignes, L. Defebvre, A. Leentjens, K. Dujardin (Lille, France)

  • Apathy as a non-motor symptom(NMS) in patients with Parkinson’s disease(PwPD) and patients with Huntington’s disease(PwHD) in Tomsk, Russia

    M. Nikitina, V. Alifirova, K. Nurzhanova, N. Center, N. Zhukova (Tomsk, Russian Federation)

  • APOE, TREM2 and LINGO1 genes: A possible implication in cognition in essential tremor in a Tunisian population

    G. Ali Barreh, A. Nasri, S. Zidi, A. Rekik, S. Mrabet, I. Kacem, M. Ben Djebara, R. Gouider (La Manouba, Tunisia)

  • Apolipoprotein E ε4 and risk of freezing of gait in early Parkinson’s disease

    R. Kim, J.S Jun, H.J Kim, B.S Jeon (Incheon, Republic of Korea)

  • Apomorphine as a Diagnostic tool to Identify Levodopa Responsive Atypical Parkinsonism

    M. Faisal, D. Sreenivasa, R. Jayachandran, R. Seetharam, R. Iyer, P. Kukkle (Bengaluru, India)

  • Apomorphine improves pulmonary function in parkinsonian patients

    I. Reuter (Giessen, Germany)

  • Apomorphine subcutaneous infusion reduces dopaminergic dosage whilst maintaining motor benefits in Parkinson’s disease: A prospective analysis of Thai Apomorphine Registry

    O. Phokaewvarangkul, K. Boonpang, R. Bhidayasiri (Bangkok, Thailand)

  • Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Effect on MDS-UPDRS Part III Subdomains

    M. Siddiqui, V. Evidente, P. Bhargava, B. Navia, E. Pappert (Winston-Salem, NC, USA)

  • Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Impact of Concomitant Antiemetics and Dopamine Agonists on Nausea and Vomiting

    A. Ellenbogen, A. Nicholas, R. Hauser, P. Bhargava, E. Pappert, B. Navia (Farmington Hills, MI, USA)

  • Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Impact on Dyskinesia

    K. Klos, J. Hui, B. Robottom, P. Bhargava, B. Navia (Tulsa, OK, USA)

  • Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Impact on Impulse Control Disorders

    A. Espay, K. Markopoulou, P. Bhargava, B. Navia (Cincinnati, OH, USA)

  • Application of a Simple Parkinson’s Disease Risk Score in a Longitudinal Population Based Cohort

    K. Marini, P. Mahlknecht, F. Tutzer, H. Stockner, A. Gasperi, A. Djamshidian-Tehrani, P. Willeit, S. Kiechl, J. Willeit, G. Rungger, A.J Noyce, A. Schrag, W. Poewe, K. Seppi (Innsbruck, Austria)

  • Application of Deep Neuronal Networks for the extraction of spectral characteristics in patients with Parkinson’s disease

    A. Maitin, A. Garcia-Tejedor, M. Castillo, I. Serrano, E. Rocon, A. Arroyo, J. Andreo, J. Romero (Pozuelo de Alarcon, Spain)

  • Application of PKG System for Objective Measurement and Early Identification in Parkinson’s Disease

    C. Lina, C. Guoen, W. Huidan, W. Yingqing, C. Ying, C. Xiaochun, Y. Qinyong (Fuzhou, China)

  • Application of substantia nigra feature extraction in the progression of Parkinson’s disease based on magnitude image of susceptibility weighted imaging

    Q. Ren, B. Zhang, J. Zhang, X. Shuai, X. Nan, Y. Ge, X. Meng, C. Zhao (Qingdao, China)

  • Approach to the patients with the hallucinations, in the Parkinson’s disease in the low-income country and environment of restricted medications and stigmas

    B. Mukhammedaminov (Tashkent, Uzbekistan)

  • Aquatic Physiotherapy increases ventilatory parameters in Parkinson’s disease

    V.L Israel, A. Silva, B. Yamaguchi (Curitiba, Brazil)

  • Are effects of Rock Steady Boxing and PD SAFExTM on the motor symptoms of Parkinson’s disease maintained long-term? – A single-blinded randomized controlled trial

    K. Sangarapillai, B. Norman, Q. Almeida (Waterloo, ON, Canada)

  • Are functional movement disorder phenotypes or age at onset correlated with perfectionist personality trait or history of abuse?

    R. Mehanna, L. Zhu, C. Bejjani (Houston, TX, USA)

  • Are New York City rail tracks harbingers for Parkinson’s disease?

    R.T Tan Morales, J. Ma, M. Salgado (Brooklyn, NY, USA)

  • Are oromotor deficits a late stage signs in Parkinson’s disease?

    P.U Upadhyay, S.G Gudwani, K.S Sharma, S.K Kumaran, R.S Sagar, R.D Dhamija (New Delhi, India)

  • Arm Swing Differences in Patients with PD and ET during Walking

    W.S Zhang, C. Gao, P.C Zhang, G. Li, S.D Chen (Shanghai, China)

  • Asleep versus Awake DBS: Real World Evidence from the Product Surveillance Registry

    M. Schiess, S. Falowski, P. Konrad, G. Plotkin, J.P Azulay, S. Navarro, A. Lopez Rios, K. Stromberg, K. Bhatia, T. Weaver (Houston, TX, USA)

  • Assessing the Safety and Tolerability of ABBV-951 (Foscarbidopa/Foslevodopa) in Advanced Parkinson’s Disease Patients During a 52-Week Phase 3 Study: Study Design and Updated Patient Baseline Characteristics

    M. Facheris, J. Streit, J. Jia, D. Standaert (North Chicago, IL, USA)

  • Assessing the screening performance of three abbreviated smell tests in Parkinson’s disease

    G. Goodwin, H. Li, A. Ismail, H. Azevedo, G. Giovannoni, A. Schrag, A. Lees, J. Cuzick, J. Bestwick, S. Auger, A. Noyce (London, United Kingdom)

  • Assessment of Real World Effectiveness: A Deep Brain Stimulation Retrospective Outcomes Study

    J. Volkmann, F. Steigerwald, M. Barbe, N. Van Dyck, R. Jain (Würzburg, Germany)

  • Association between actively and passively monitored gait in early Parkinson’s disease

    E. Volkova-Volkmar, A. Thomann, B. van Lier, D. Wolf, G. Pointeau, Y.P Zhang Schärer, W.Y Cheng, C. Simillion, G. Pagano, W. Zago, C. Gossens, F. Lipsmeier, K. Taylor, M. Lindemann (Basel, Switzerland)

  • Association between actively and passively monitored hand gestures in early Parkinson’s disease

    E. Volkova-Volkmar, A. Thomann, B. van Lier, D. Wolf, G. Pointeau, Y.P Zhang Schärer, W.Y Cheng, C. Simillion, G. Pagano, W. Zago, C. Gossens, F. Lipsmeier, K. Taylor, M. Lindemann (Basel, Switzerland)

  • Association between BDNF Val66Met polymorphism and mild behavioral impairment in patients with Parkinson’s patients

    M. Ramezani, J. Ruskey, K. Martens, E. Leveille, Z. Javer, I. Kathol, M. Kibreab, T. Hammer, J. Cheetham, J. Sarna, D. Martino, G. Pfeffer, Z. Gan-Or, Z. Ismail, O. Monchi (Calgary, AB, Canada)

  • Association Between Diet & Parkinson’s Disease Progression

    L. Mischley, J. Farahnik (Kenmore, WA, USA)

  • Association between essential tremor, constipation, and the risk of developing Parkinson’s disease

    C. Reynolds, M. Gupta, M. Sandulescu (Danville, PA, USA)

  • Association Between Fatigue, Depression and Sleep Disorders in People with Parkinson’s Disease

    G. Xavier-Souza, I. Alves, A. Mendoza, L. Almeida, G. Valença (Salvador, Brazil)

  • Association between Glutamic Acid Decarboxylase Antibodies (Anti-GADs) and Parkinsonism: Case Report

    W. Trillo Alvarez, J. Molina Acosta, J. Medina Suarez, A. Escalante Mercado, M. Torres Medina, E. Carrillo Monteagudo, G. Calderon Paiva, J. Valdivia Pinto, M. Mejia Vega (Arequipa, Peru)

  • Association between impulse control disorders and depression in drug-naïve Parkinson’s disease

    A. Karukote, S. Thakolwiboon, P. Julayanont (Lubbock, TX, USA)

  • Association between motor symptoms and striatal VMAT2 binding in PD: a PET study

    S.Y Liu, H.W Qiao, C.Y Qi, Z.Q Gu, O. Barret, K. Marek, G. Tamagnan, P. Chan (Beijing, China)

  • Association between non-motor symptoms and severity of axial symptoms in patients with Parkinson’s disease

    H.A González-Usigli, A. Montaño-Serrano, I.E Berumen-Ocegueda, B. Contreras-Haro (Guadalajara, Mexico)

  • Association between prediagnostic symptoms and patterns of treatment initiation in people with Parkinson´s disease in the United Kingdom

    L. Rutten-Jacobs, S. Roumpanis, Y. Liu, P. Coloma (Basel, Switzerland)

  • Association between SNCA and clinical phenotypes of Parkinson’s disease in southern Chinese

    G. Li, SS. Cui, P. Huang, S.D Chen, YY. Tan (Shanghai, China)

  • Association between the number of CAG repetitions and cognitive performance in Huntington’s disease in patients of the National Institute of Neurology and Neurosurgery “MVS”

    D. Gasca-Saldaña, A. Vega-Rosas, G. Palma-Cordero, O. Castellanos-Maya (CDMX, Mexico)

  • Association Between Ventricle/Brain Volumes and Mobility Metrics in Parkinson’s Disease

    A. Ragothaman, A. Giritharan, M. Mancini, O. Miranda-Dominguez, D. Fair, J. Nutt, F. Horak (Portland, OR, USA)

  • Association between ZNF184 and symptoms of Parkinson’s disease in southern Chinese

    B.Z Zhang, G.L Li (shanghai, China)

  • Association of environmental exposure to herbicides, fungicides, and insecticides used in agriculture with incidence of Parkinson’s disease in the French general population

    L. Perrin, J. Spinosi, L. Chaperon, D. Jezewski-Serra, M. El Yamani, F. Moisan, A. Elbaz (Villejuif, France)

  • Association of gait domains with cognitive and neuropsychiatric domains in patients with Parkinson’s disease: A Brazilian exploratory study

    E. Lirani-Silva, R. Vitorio, D. Orcioli-Silva, P. Nobrega-Souza, N. Conceição, V. Beretta, L. Gobbi (Portland, OR, USA)

  • Association of Interleukin (IL)-2 and IL2RA gene polymorphisms with Parkinson’s disease in Taiwan

    T. Liu, Y. Wu, Y. Chen, H. Fung, C. Chen (Taoyuan, Taiwan)

  • Association of TTPA mutation and peripheral nerve involvement in Gait disturbances in Ataxia With Vitamin E Deficiency (AVED)

    D. dos Santos, C. de Oliveira, F. Kok (Sao Paulo, Brazil)

  • Associations between balance confidence, gait, postural stability, and muscle strength in people with Parkinson’s disease

    B. Donmez Colakoglu, F.K Cekok, T. Kahraman, G. Duran, D. Yerlikaya, G. Yener, A. Genc (Izmir, Turkey)

  • Associations between subjective and objective cognitive decline in Parkinson’s disease

    K. Mills, R. Schneider, D. Oaks, M. Saint-Hilaire, R. Hauser, A. Lange, K. Blindauer, M. Halverson, G. Ross, I. Litvan, S. Eberly, T. Simuni, C. Marras (Baltimore, MD, USA)

  • Asymmetrical cochlear dysfunction as a lateralized non-motor feature in Parkinson’s disease

    R. Cerroni, A. Viziano, R. Sisto, A. Moleti, N.B Mercuri, A. Stefani, M. Pierantozzi (Rome, Italy)

  • Asymmetrical resting legs tremor induced by levosulpiride

    W. Yoon (Seoul, Republic of Korea)

  • Ataxia and action myoclonus with biallelic mutations in ATP13A2 gene

    A. Sánchez-Rodríguez, I. González-Aramburu, M. Sierra, A.L Pelayo-Negro, M. Corral-Juan, X. Farré, I. Sánchez, A. Matilla-Dueñas, J. Infante (Santander, Spain)

  • Attitudes of Care Partners Toward Medications for Parkinson’s Disease Psychosis

    S. Mantri, S. Albert, E. Klawson, L. Alzyoud, M. Daeschler, C. Kopil, C. Marras, L. Chahine (Toronto, ON, Canada)

  • Attitudes towards disease in patients with essential tremor

    Y. Trufanov, N. Svyrydova, V. Sereda, V. Svistun, A. Yanchak, I. Zarashchak (Kyiv, Ukraine)

  • Atypical alternating hemiplegia of childhood in Korea: A case report

    C. Shin, H. Kim, B. Jeon (Daejeon, Republic of Korea)

  • Atypical parkinsonism due to a mutation in the SLC9A6 gene

    L. Muñoz-Delgado, S. Jesús, D. Macías-García, A.D Adarmes-Gómez, F. Pérez-Errazquin, F. Carrillo, P. Mir (Seville, Spain)

  • Atypical Psychogenic Nonepileptic Seizure (PNES) preceding Multiple System Atrophy (MSA)

    A. Shahinian, T. Mehta, A. Betcher, P. Janda, J. Mahajan, A. Vickers (Las Vegas, NV, USA)

  • Automated Capture of Deep Brain Stimulation Settings & Clinical Outcomes

    K. Castell, C. Butson (Salt Lake City, UT, USA)

  • Automated classification of neurodegenerative parkinsonian syndromes using multimodal magnetic resonance imaging in a clinical setting

    L. Chougar, J. Faouzi, N. Pyatigorskaya, O. Colliot, S. Lehéricy (Paris, France)

  • Automated pattern based classification in neuropathology proven parkinsonism

    K. Schindlbeck, D. Gupta, C. Tang, S. O'Shea, K. Poston, V. Dhawan, J.P Vonsattel, S. Fahn, D. Eidelberg (New York, NY, USA)

  • Automatic classification of abnormal movement in Huntington’s disease using wearable sensors and machine learning

    S. Aradi, R. Pierson, B. Scheid, S. Baldassano, B. Litt, P. Gonzalez-Alegre (Tampa, FL, USA)

  • Automatic Detection of Nigrosome Degeneration in Susceptibility-Weighted MRI for Computer-Aided Diagnosis of Parkinson’s Disease Using Machine Learning

    B. Garcia-Santa Cruz, A. Husch, F. Hertel (Luxembourg, Luxembourg)

  • Autonomic symptoms as biomarkers in REM Sleep Behavior Disorder and Parkinson’s disease

    W. Hermann, L. Ecke, D. Wittig, D. Hausbrand, M. Brandt, H. Reichmann, A. Storch, T. Ziemssen (Dresden, Germany)

  • Autosomal recessive spastic ataxia of Charlevoix-Saguenay: A Mexican case report

    D. Gasca Saldaña, M. Boll-Woehrlen, D. Dávila-Ortiz, C. Alaez-Verson, L. Flores Dominguez, P. Zamora Alaniz, C. Molina-Garay, C. Dehesa, M. Jiménez, K. Carrillo Sánchez, A. Vega-Rosas (Mexico City, Mexico)

  • Auxilin knockout mice: a model for Parkinsonism with dopamine dysregulation and synucleinopathy

    V. DJ, S. Chandra (New Haven, CT, USA)

  • Axial myoclonus and cerebellar ataxia in a patient with mutation in ADCK3

    M. Gultekin (Kayseri, Turkey)

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